I take medication daily for GERD and it's fine. Warfarin can increase her GERD symptoms and cause some GI upset. Honestly, most medications can affect your INR or interact w/ warfarin so it really becomes a matter of just knowing that and staying on top of your INR.

Also a pharmacist is a good resource for helping you figure out what meds interact and which have a higher risk for affecting her INR. It's really not always a matter of the drug not being safe because you're on warfarin but rather how it can interact.

... I just checked if my GERD meds (dexlansoprazole) have a possible interaction with warfarin and it does. So did the drug I was previously for GERD (Rabeprazole).

I've tried to not take them, before being on warfarin, with not great results. My GERD is not diet related so it's not like I an change my diet to address it. I also had my gallbladder out a few years ago which made it worse because that caused bile reflux. So I'd be pretty miserable if I didn't take something.

Basically, I think any proton pump inhibitors, which is what these drugs are, could possibly interact, but again, that doesn't mean you can't take them. It means to be mindful so if you notice any changes to your INR or bleeding, you call your doc. Everything about being on warfarin is just being aware.

I am on Warfarin and my doctor gave me Nexium..can get it over the counter..does a good job..takes a few days to kick in though..

Nexium has the same possible interaction as the other drugs listed above.

Does she take the medication every day or is it only occasionally? If she takes it daily, her warfarin dose can be adjusted to deal with any interactions. If a med tends to move the INR up, for example, you'll adjust to take a smaller dose to counteract that.

It becomes more challenging if you only take the medication occasionally. Then, it may have more of an impact, but it might just move the INR from 2.3 to 2.6, so that's not an issue.

Really, you'd just have to take the med (after clearing it with a doc, pharmacist, whatever) and keep an eye on the INR to see if it goes up, down, or whatever. Then, the warfarin dose can be adjusted so both meds can be taken safely.

Hi. I don't have any idea what acid reflux will work with coumadin but I know if you call a pharmacist they would know even better than a dr. would know. I am ALWAYS calling my pharmacist because I take a LOT of meds, I have so much going wrong with my body. But really, call your pharmacist, they know better than anybody what will interact best with whatever you are already on. As far as acid reflux it's really important to get on SOMETHING for it because I know people who have gotten throat cancer from acid reflux and that is probably worse than not taking any acid reflux medication at all...