This just shows what a HUGE development this has been, its been posted for the third time, I think we are gonna remember this one as a BIG milestone development in the treatment of MS :)

http://www.dailystrength.org/c/Multiple_Sclerosis_MS/forum/8928366-ampyra

http://www.dailystrength.org/c/Multiple-Sclerosis-MS/forum/In-The-News/8924343-fampridinesrammaya-approved-fda

oh cool i have not heared about that. i will ask my doctor about it. i would love 2 take a pill instead of shots i already feel like a pin cushion because i give myself insulin shots 2 times a day.

kimmie, it doesn't take the the place of the "pin cushion" disease modification meds, it is symptom treatment taken along with the pincushion diseae modifying meds....the oral drugs that will replace tne pin cushion meds are set to copm out lat this year ot next year. The two closest oral meds to be released are Fingolomid & Cladribine

http://www.dailystrength.org/groups/positivemssupport/discussions/messages/8918914

In Reply #5 of this thread charchar describes the history of Ampyra.

http://www.dailystrength.org/c/Multiple_Sclerosis_MS/forum/8928366-ampyra

But Apyra is symptom treatment to help with walking & maybe it will help with other symptoms too!

But having LDNLarry post of its existence, as he is a strong proponent of LDN ,was important so others on LDN know it exist for symptom management....

I got to think about LDN after Larry posted it.

A BIG argument for LDN is that because it was not developed by drug manufactures, the expensive trials needed to get it approved by the FDA that was not financed by the pharmaceuticals, and goes by word of mouth anecdotal evidence only,therefore LDN was never approved by the FDA as an MS treatment because of that.

Ampera disproves that LDN argument.

Ampyra started as 4-AP that people could get from compounding pharmacies---like LDN is now.

Then even though Ampyra was not developed by pharmaceuticals, it was an already in existence chemical that was found to be helpful in MS....

A pharmaceutical company ceased it & changed the method of delivery did the expensive trials needed to get FDA approval and now will be marketing it. It was a torturous name change journey to compete the path.

It started as a bird poison, was found to be helpful in MS, people found out by word of moth and got it from a compounding pharmacy as 4-ap.

It was taken up to do the trials the name change whent from,

4ap->Fingolomid-> Fingolomid-SR -> Amaya ->Ampyra(FDA approved)

So The LDN argunent that LDN is effective it just doesn't have the trials to prove it....is somewhat weakened by the story of Amprya.

The LDN argument different from conventional MS treatment is whether the immune system has to be strengthened.

LDN- strenghthens the immune system.
Interferons - weaken, suppress or modifies the immune system
Copaxone acts with the antigens the immune system responds to.

So the story of Ampyra helps differentiate the argument for LDN. That LDN is not an approved medication for MS because there are no expensive trials to get FDA approval for it...well the story of Ampyra disproves that.

The argument for LDN instead of interferons or copaxone would be based upon strengthen the immune system alone

Ampyra is a.symptom treating med that was not developed by a pharmesceutical company and even so, a pharmescuetical company jumped on it, did the trial and will now market it.

I have read that LDN helps with symptoms a lot too, but no pharmeusitical company has jumped on it to market it....

And changing the something small in a med, deliverary, color of the pill whatever is a common method of a drug company to get their patents protected. Not being developed by a drug company is not a reason for not doing the trial and marketing it. and making $ of it. UNLESS....

And there is the oral pill form of marajauna, that is in use in Canada I think...also another one that disproves the LDN argument that LDN just doesn't have the expensive trials which is why LDN is not an approved MS treatment....

CORRECTION:::

I wish they gave the ability to edit. I am always confusing the wods Fingolomid with Fampridine. Fampridene no longer it exists. It was once a word for Ampyra.
Fingolomid is an oral drugg that is waiting FDA approval and will replace the disease modifying meds.

4ap-> Fampridine -> Fampridine-SR -> Amaya -> Ampyra(FDA Apprioved)

-vs-

Fingolomid - oral medication for MS waiting for FDA approval.

I'm lucky the word Fampridine will go away and only be known by "old timers". I would have a tough time getting it confused if it stayed.

I just found out that this drug won't be available until March. Good luck in getting it when it comes out.

I'm glad my LDN costs me only $21.14 a month for 3.0 or $31.71 for 4.5

LDN works with more than just MS, LDN is not an MS issue

more people's lives are being saved with cancers, autism, crohn's and fibro than MS.

The world economy can do what it wants, until then, it's LDN for me. Going on 7 yrs now. I don't care about the politics

I am currently in this study, we are open label now but i did not here that it would be approved and available in March. I will be seeing my Neurologist early next month. That would be great if it will be.

There is a Webcast on Fapridine, Ampyra at the NMS site, that you might find interesting...

http://www.nationalmssociety.org/multimedia-library/webcasts--podcasts/ampyra-a-new-medication-to-improve-walking/index.aspx

I think this is what I took, Larry. The drug I was allergic to - full name aminopyridine.