I'm up to 400 mg a night, and I sleep like a baby.
Knocks me out, but I wake up alert and well rested.
Sometimes I get hypomanic and I need to bump it up to 600 mg.

Hi I have been on seroquel 300mg for a year, It makes me very drowsy so I take it just before bed. I have a hangover in am if my bedtime isnt early enough. My doc is gradually decreasing..225mg.

BE CAREFUL WITH SEROQUEL SOME PEOPLE HAVE EXPERIENCE SUICIDAL THOUGHTS.OR ANGER.EVERYONE IS DIFFERENT,AND GETS DIFFERENT RESULTS. JUST BE AWARE AND COMUNICATE WITH YOUR DOCTOR ABOUT YOUR REACTIONS AND SYMPTOMS.ALWAYS RESEARCH PROS AND CONS OF YOUR MEDS.LOTS OF LUCK.

used to take it for sleep and acute mania (25 mg) knocked me out and made me feel like a had a hangover the next day

i was on 400mg twice a day and would fall asleep in my plate of food at dinner. i stopped taking it .

i have been taking seroquel for a few years and i take 500mg-700mg a night. to be honest sometimes it works very well and sometimes it doesnt but for me, its definately better than nothing! your body builds up a tolerance to it very quickly which is why they have already upped your dose several times and also why my dose is so high. you say you have only been taking it for a couple weeks? you may need a dose increase again and you will experience the morning hangover for a while until you get used to it. that does get better with time. bunnyfig is right about being cautious with seroquel. as with any med, just because it works for me doesnt mean its the best for you and there are always those risks. as for your dose of 100mg, thats not really a high dose and im living proof of that fact. ive met people who take even more than i do and still function. hang in there!

I take 50 at night to sleep..works

I take 25mg at bedtime and it knocks me right out, I have to give myself at least 9 hours before I have to be functional or I'm groggy and miserable. I've learned this the hard way, after missing two Saturday mornings of work because I wanted to stay up and play on a Friday night. I read somewhere that it's better for sleep in the low doses and better for the anti-psychotic properties at high doses, but I don't know if that's true.

I started off with 25mg completely knocking me out, but I was in a depressive phase. Later, in the hypo-manic phase, I'm now up to 75mg, and it seems OK. It does feel like the body gets used to it over time, and the side-effects are less.

BTW, people take up to 1000mg/day and even more, but my doctor says those are severely ill people.

I am in love with the over the counter "vitamin" called melatonin.It comes in 1,3 or 5mg.I started out on 5 then after 1week went to 3 and now I only need to take it occasionally.It is a lifesaver and it doesnt effect any meds.and no side effects.Works fast (about 30 minutes after taking it)I would recommend it to anyone who cant sleep!Try it and let me know ok?

ive been on seroquel fro almost 3 years. i take 900mg at night and yes it knocks me out. i can't sleep without it. its sort of like my security blanket....

I have been taking Seroquel, for bi-polar and to help me sleep, since november, 2007, and also, lamictol. Doctor started me off with 100 mg, then upped it to 200, then 300, then 400, but i was sleeping around the clock, so he lowered it back to 200, but i think i am getting tolerant of it so he raised it back up to 300. I get very argumentative, express suicidal thought, and a few times almost succeeded at it. Only thing is, I just got married to a wonderful, very patient man, whom i adore, and i wish all this would stop, so i could really enjoy my marriage.

I take 300mgs on nights that I know Im going to have trouble sleeping. It works great and I wake feeling rested.

I think it starts at 10mgs up to 400mgs, which I also have. Pdoc thought it would be a good idea incase the 300 didnt work.

My 9 yr old takes 50 mg's AM & PM. Both for the anti-mania, and to sleep at night. It slowes him down some during the day but he functions well enough to get A's on almost all of his tests. To sleep he takes
.3 mg's of clonidine. But as you know, the combination that is right for you is diffrent than anyone else.

I took 100mgs a night for sleep for awhile. My doc won't give it to me anymore, though. I don't know why.