Hi. I haven't posted on a while. I take 6 tablets of MTX on Saturday and the daily folic acid. I have been very lucky in that I have no real side effects - some hair loss, but I had such a thick head of hair that it's almost a blessing. I was doing really well for a long time, but the colder weather seems to be affecting my joints - they all seem to want to take a turn with the achiness. Also, we had some really bad weather (tornado like) here over the weekend, and I'm wondering if the barometric pressure has something to do with it.

Eighteen months worth of injections, .6 ml, equal to 6 pills. I take it right before going to bed, hoping to sleep through the worst of it. It does add to fatigue, and my stomach usually isn't great the next day, but it is tolerable.

I've been taking MTX since October of this year. I started off on the pills but they made me rightfully ill, which i hear is common. I now take it subq .6ml

Been on it sense August of 2012 I take 6 pills on Thursday and have no real side affects except and I have not mention this yet to the Roomy but I have had loss of appetite were I have to remind myself to eat whether I am hungry or not.

Took my second dose on Friday. I am only taking 4/week, so I do 2 at breakfast & 2 at dinner. So far, so good. The first week, a few days later I felt very fatigued one evening, but that could be lack of/wrong type of food, or just about anything. Only time will tell -- Doc says we will eventually ramp up to 10 pills. I typically have had a "cast iron" stomach, so hopefully that will continue to be the case!

Methotrexate tablets for 2 years now. Started out with 4 tablets, then to 7, then reduced again to 4 because of liver enzyme tests. Never had an adverse reaction at all.

Been on it for 12 weeks. Take 15mg every Friday night and folic acid daily. No real side effects other than sometimes being tired the next day, but that could be work schedule as well. Not sure if it's working yet-still have flares in the knees, hand and wrists and have a nasty tendonitis flare in my wrist/hand as well. Appt on Thursday, so we'll see what the numbers look like.

wowwww 51% you ahve never had any serious issues from being on it for that long ?/ I was wondering how long a person could be on it ...

I have been on MTX for 3 weeks. I take 10 mg, injectable. I know the doctor wants to increase it to 12.5 mg after my labs next week and then again after labs in January assuming labs look good.

I get terrible fatigue from the MTX. I take it very early on Friday mornings and work form home as long as I can. I can feel the fatigue/brain fog/weakness starting about 1.5 hours after I take it. By 4-6 hours in I am done for and must stop working and sleep. I am wiped out on Saturday as well but feel better for the most part on Sunday. I have also noticed a lack of appetite for a day or two after taking it. Some weight loss would not be a bad thing for me!

I was on injectable MTX for about 2 years. I started having sensations of burning and stinging in my lower legs and feet. Bottom line was that MTX caused a serious side effect of peripheral neuropathy in my lower extremities. Glad my RA doc sent me to a neurologist. Two years later, I still have the neuropathy. Initially I thought it was restless leg syndrome as my mom and brother have it. So be sure and report ANY new symptoms!

I was on MTX for about 6 months. Last week was my last dose. Had to quit because it made sick all week long. Was taking 6 pills a week, along with folic acid daily.

Be careful with mtx, my Husband took this for less then a yr and developed lung problems, nodules. Now he has copd and hard time breathing. And it made himvery sick. One weekly injection. Bittersweet. Goodluck to you.

I've been on MTX now for about 3 months. I take 15mg or 6 2.5mg tablets every Sunday. I only started feeling some moderate nausea from Monday until about Tuesday night after about the 2nd month. So my rheumy advised to cut into 2 parts on Sunday 3 pills for lunch 3 pills for dinner & it seems to work. Now it's more like mild nausea only on Monday then done by Tuesday morning.

I was also having some intense itching around my forearms, size of nostrils, forehead & sideburn area but started doing a home remedy sea salt facial wash twice a day & that's taken care of the itching & flaking on the face, the forearm itching seems to have just taken care of itself.

Other than that I may be slightly drowsy on Sunday afternoon but no major fatigue throughout the week.

I took for 3 years on and off. I kept feeling tired and my pain in joints felt like they were on fire 4 days of the week, I hated feeling that sick. He kept upping dosage. Got to 10, I wanted to die. I injected it.

Stuff is awful, I rather suffer. Bleh I bet I would suffer less drinking gasoline. It was awful for me. Even with folic acid, nothing helped.

I did well without. =)

Lin

I've had my 9th dose of methotrexate and so far things have been going better than I expected. I started with four pills a week and now I'm taking 6 pills along with folic acid daily. I would notice some of the fatigue after the first couple of days of taking my dose but that seems to have faded. I had one bad day where I was nauseated and very tired 2 days after taking my MTX but maybe that was due to something else. I take my full dose on Friday with dinner and lots of water. I think I'm finally
feeling better overall so I'm pleased so far. Hope you get relief too.