I have not but I am new to this. I was started on Coumadin.

I think there are a few posts from people who had issues with Xarelto and were hoping to switch off, although I don't know which med they finally switched to. Definitely run some searches ... if you're having issues with Xarelto, there are definitely enough other meds on the market at this point, that you ought to be able to try something else.

I don't think it's unheard of.

Here's an article from a few years ago that discusses the transition to Xarelto from other anticoagulants and the transition from Xarelto to other anticoagulants.

http://professionalsblog.clotconnect.org/wp-content/uploads/2012/05/UNC-Xarelto-2012.pdf

There are people that have switched back to Coumadin for various reasons. A majority of those patients have APS.

For me, after having been on Coumadin for about 20 years, I have been pleased with Xarelto so far (switched to it back in November 2012). Less bleeding issues when having that occasion fall on the Mountain Bike, less fatigue and no food interactions as far as Vitamin K. But, it's not for everyone.

R/Tom

I might have missed in the info but why do APS people switch back to Coumidin?

I'm interested about the APS too, because didn't we have a guy on one of the boards a few months ago who was having problems clotting again and had been taking Xarelto? But he also had a clotting disorder, I think it was APS. I had suggested to him at the time that perhaps not enough research had yet been done to know how to dose Xarelto for someone with APS, since their anticoagulation level needs to be higher than normal therapeutic.