I've taken the drug, twice actually. I didn't notice any mood shifts. My coworkers said that I had crazy mood swings, but I think they just really didn't want me to take the pills. You know the look you get when people find out you've been presribed a diet pill, then it's followed by "well, just be careful those things are addictive." Then you you snap back with, "So is smoking, but I see you're still doing it."... stupid booger heads. Suddenly you get labeled as having mood swings, go figure.

If it's serious enough to make you concerned then bring it up with your dr. I was very open with my dr about everything. I was afraid of the pills and what could happen to me. However, my dr is GREAT and takes everything I bring up seriously and reassured me that I was fine and just reacting to circumstances rather than having a break down from taking diet pills.

On a side note. July 2nd I was 266 pounds. I took the pills for three months, and tonight I stepped on the scale at work (mostly out of curosity) and I'm at 207 pounds. The pills really helped me to learn what full really felt like. Which helped me to change what and how I eat.

I have taken them in the past and will be starting to take them again as I need to lose a bit more weight for my leg. I did get hyper with them as in more energy but I never had mood swings on them.

I have been on these pill 4 times...they are really great for loosing weight..I also have asthma and this last time I went on them they didn't work as good..made me feel sleepy..I think it is my other meds..I didn't have any mood swings..had alot of energy and they made me feel good..but that was when I was working..Good luck to you one these pills..They are great@loosing weight..

i have bipolar so i can't take things like that... i'd consult a doctor- or just stop taking it, see how you feel, then start taking it again, keeping track of how you feel each day, what dose you take, etc. (i keep a mood chart like this) and then you can see if there's an actual correlation or not.