Myasthenia Gravis Support Group

Myasthenia gravis (MG) is a neuromuscular disease leading to fluctuating muscle weakness and fatiguability. The hallmark of myasthenia gravis is muscle weakness that increases during periods of activity and improves after periods of rest. Although myasthenia gravis may affect any voluntary muscle, muscles that control eye and eyelid movement, facial expression, and...

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Muscles & Bones
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Achy Joints & Bones

ShanAlis
ShanAlis
I am on a low dose of prednisone, 10/15 alternate days. Sometimes, which this sometimes is mostly at night i feel like my bones and my legs ache so bad (growing pain feeling in my legs), and i feel like my bones are so weak they could snap in half if im not careful. When i wake up in the morning this feeling is gone... its so strange. Does anyone else experience this? I am also on Imuran and mestinon.

Ways to avoid this?

I take calcium and vitamin d supplement as well as omega 3 and vitamin b complex daily.

Thanks
deleted_user
deleted_user
Leg pain is a "less common" side effect of prednisone on a huge list of side effects. The advice is "call your doctor" if the side effect occurs and see what she recommends.

If you search on
prednisone leg pain
with Google, you will see a lot of folks complaining about it--and some of the suggestions for dealing with it--from drinking lots of water, putting your legs on a pillow, and so on. I would start with my doc.
angepugin
angepugin
It may not be the prednisone causing your achy joints and legs so like Russ suggests you should probabaly discuss it with your doc. I know that prednisone can reduce potassium levels though which can cause cramps and achy muscles. Have you had your potassium levels checked?
bweeds
bweeds
Starting with your doc is a good idea, but sometimes what we experience isn't widely known or accepted. Many people on line experience cramps with falling Mestinon levels. There are several discussions that you can find in the links group under "Fasciculations and Cramps." That discussion is currently on the second page of the Links Group and that discussion also has a link to the PNH syndromes which is another possibility.
I'm sorry you are experiencing this. It can be difficult to sort out. b.
larissam
larissam
I often experience the same discomfort. I am more achy the more active. For me an increase in activity equals an increased need for water. Add this to your neuro list of questions & I hope you soon find what works for you.
Larissa
Barbel
Barbel
I have achy legs if I don't take my apple cider vinegar pills at night. You can google apple cider vinegar and leg cramps. Also, as always , it 's good to talk to your doc. Good luck.
becwithkids
becwithkids
I have issues with my legs and am on prednisone as well.

Have you looked at the possibility of Restless Leg Syndrome?

Mine came on about 6 or 7 months ago and made it very difficult (sometimes impossible) to sleep at night. I had actual pain in my knees (stairs!) during the day as well.
Now that I am being treated for RLS (a half a ropinirole at bedtime) I can fall asleep without them bothering me... I do not have the pain in my knees during the daytime either!
ps. Tapering prednisone made my leg issues worse for the first few days of a step down in the dose!
Love, Becca