My feeling about this posting is that results reported by pharmaceuticals and real world can be miles apart, not just on triple therapy but all drugs.
I think most sensible folks would be interested in that.

Agree with you Kramer! But the SVR issue makes it to the Net most times, and the posters are all patients, people who did the treatment and not the Pharma. I dont think we know anyone here who had a relapse after 6 months of SVR on the new drugs. Even as they are miserable , they worked for many folks with out any relapse passed that marker. And that is what we are debating.

Now you clarify yourself Bika!! You need to be more specific before you make anymore of those vague and very generalized statements...

Hence the reason why I challenged your initial claim and you are the last person who's going to teach me anything about liver transplantation & it's effectiveness in getting rid of HCV!
So STFU and stop spewing out the obvious!!!

Another fact you don't know is the fact that on mono therapy, we were given much higher doses and more frequently on a weekly basis as opposed to once a week and that was also true with the initial Ifn/riba combo before the switch to pegylated Ifn...

Let's face it Bika, you don't have your facts straight when you post and you only sometimes get them together enough to where they're coherent enough to understand afterwards just exactly what your point is and I'm not the only one in here that notices this...

So please get your facts straight and at the very least, you need to be much more specific & detailed with your data because if you don't then many will not at all understand what you're talking about, and also so that I don't have constantly ask for clarification or challenge whatever it is that you initially claim or some of your posts! Because contrary to what you think, I really don't like to be coming off as if I'm picking on you at all...

Btw, 33% per cent is not many many folks dude!! It may seem to be that way in here but then again, you haven't been here that long and for awhile there, you were totally MIA because there have been quite a few that have relapsed - not many but a few who have relapsed after 6 months on triple and some even longer than that!

Still, there's not going to be a significant population of patients that have relapsed after two years yet because of the fact that triple therapy has only been around since 2011 so, the jury is still out...

And finally, hepcat is correct when she says: "So who cares what the REAL damned cure rate is for triple?" since the new DAA's will be starting to become approved and appear out in the market for widespread use even though there may be some restrictions that can be worked around as early as December -2013 or January of 2014!!!

So I hope everybody that has treated on triple do remain cleared of the virus and yet as I mentioned earlier, the jury is still out on that treatment as it will also be the case with the newer interferon free DAA's that are being ready for approval -and ready hopefully for prime time!!! We shall find out soon enough!

Respectfully,
Henry

hi hepcat, you probably posted it before, but i would like to know what is your il28b gene, mine is TT so am concerned with the new treatment, and may not have to be.

Wow on this thread. Hadn't seen it until now. A newbie walking into it would sure be blown away by the complexity.

Hey hepcat haven't seen you around in ages. Hope you're well. Agree with who cares about triple cure rates too and not touching that crap with a 10' foot pole. I had just scanned through a few of my journals (all private) during the last few months of my tx and I was so frequently depressed and utterly miserable. Yeah new stuff needs to come for sure sans interferon and riba. Such nastiness. Joe I don't know how you did it 3 times and Hank wow! I knew you've done it much and were often on maintenance interferon. You might still be now. I know if I was faced with life or death that would change my thinking. But unless faced with that choice, I see your 10 feet and raise the pole another 10.

Within the history of the biotechnology sector, few franchises have gone from blockbuster status to peak to decline as quickly as that of Incivek, Vertex Pharmaceuticals' (VRTX) blockbuster treatment for Hepatitis C (HCV). Once it was approved in May 2011, sales of Incivek quickly soared past $1 billion as patients sought new methods of treating HCV, now set to decline in 2013 as new HCV treatments, led by Gilead Sciences' (GILD) sofosbuvir, supplant it. However, as the sun sets on Incivek, it's rising on another two franchises, which are poised to deliver profits to Vertex investors in 2013 and beyond.

Vertex's Q4 2012 results highlight the decline of Incivek. Q4 Incivek sales of $222.8 million fell by over 51% from the year-ago quarter as fewer patients chose to use Incivek; newer, more advanced HCV therapies are on their way to FDA approval.

http://seekingalpha.com/article/1273771-vertex-the-sun-sets-on-incivek-rises-on-its-cf-franchise

Hah, my Triple Treatment was a real Twilight Zone experience for me, but I used Victrelis, which has 4 week "lead in " with just the Pegylated Interferon and 1,200 mgs of Ribavirin,ad I was Undetected, at the end of this 4 week time period, before the Victrelis was introduced, so I was fairly confident, due to this fact, and also, I took those 4 Victrelis pills, every 8 hrs on the dot, for the whole 24 weeks, which I'm sure helped.
I blame slow or no response to Interferon, and Riba and Inf reduction, due to anemia issue, to the failures I have observed in other Triple Treaters. I never did get an ILB28 test done, so Icant factor that in.
I did feel like I was on the verge of death, from 10 minutes after I took my first 4 pills of Victrelis, to the bitter end of my 28 weeks. My worst side effect was I got the 24 hour stomach flu THREE friggin times, after the Victrelis was started, perhaps from my lack of Eosinophils, which are white cells responsible for attacking intestinal parasites (I think, lol) eeeewwww!!

But by damn, girl... you DID it; you made it through!

Congratulations!