I am almost 3 weeks on Savella. I took the titration pack for 2 weeks and now take 2 50mg doses per day. I am tapering off of the Cymbalta. So far it has worked really well. Pain reduction has been good and I have lots more energy. The first week or so, I had nausea somewhat...be sure to take after food.

I still take Lyrica and plan to continue with it and the Savella. I will know more when I am off the Cymbalta completely.

I am on month #2, so far so good.

Been on since late June. The first two weeks brought increasing nausea as the dose got higher - be sure to take it with food. Other than that, I've gotten good pain relief - tapered off the Tramadol (that was a lot harder than the Savella) and still doing well.

Increased alertness, energy, and pain relief - it's been good for me.

I've been taking Savella for the last 8 months - 50 mg morning, 50 mg night - and have had positive results. It's helped reduce my overall body pain significantly. It hasn't helped cut the muscle spasms and acute muscle pain in my neck, shoulder and back though.

I've tried Cymbalta and Lyrica, and Savella is the only med that has helped my global fibro pain without really bad side effects. The worst side effect for me is nausea.

My doctor and I used several titration packs to increase the dose really slowly over the course of a couple months. This helped my body, which is very sensitive to meds in general, get used to Savella and lessened the nausea. I agree with Pammyann and PeaceN2You, I always take Savella with food - and this seems to help the nausea. Good luck, hope Savella helps you!

Wow, I read through some other posts & I cannot wait to get through this titration pack! Everyone sounds so energetic & positive :) I have 3 young kids, so some energy and mental alertness will be much welcomed!!

I am on day 5. I have had nausea from day two and it has increased to me throwing up last night. Oh well. I am going to keep taking it and see what happens. As my dosage increases I muscle ache wise feel better. Took me off nortriptylin so I am now sleeping as well as I was but maybe that will get better. Hang in there!

I will get nausea if I don't take it with food. Also, I noticed some sweating, but haven't had any for a few days. I had the sweating on Cymbalta too. I feel more mentally alert which is wonderful.

Yes I was unable to take it after noon becaus it wired me.....my experience was NOT a good one..my blood pressure spiked ...i was hospitilized twice as the docs thought i was having mini stokes the docs in the hospital NEVER considered the fact it was the savella itwas my NP that took me off it i was on it when it was just approved here in th US Im sure they tweeked the doses if you get forgetful PLEASE tell your doc!!!

I have been on Savella for six weeks. I take 50mg twice a day and I got on my knees and praised the Lord! I know that Savella works in about one third of the cases. I have increased energy and I dont have any more pain. I have some days that I am uncomfortable which I call a 0.1 on the pain scale. I used to be an eight. I am so happy. I am also going to massage therapy and a great chiropractor. I used to have a good day a month. I now have only 2 bad days a month. I would tell anyone to try this. I didnt have ANY side effects. Not like lyrica and cymbalta. This is my miracle!

Just started on Savella this eve--my doc gave me nausea meds to go along with it just incase--sounds like they may be needed. I am really feeling positive about this med though since reading all of the other posts. I would love to have some pain relief and my energy back! I will continue to read your posts and I hope that each of you continue to do well!

I'm now on my 3rd month of Savella and feel it's helpful but definitely not a cure all on it's own.

Hang in there for the first few weeks as it can be really rough with side effects but they do go away. I had severe headaches, nausea, dizziness, loss of appetite for the first 3 wks.

After the third week, side effects had stopped and I'm on a steady dose of 50mg 2x per day. As another poster said, do take it with or after food. Don't try to take your morning dose on an empty stomach, even after you've been on it awhile.

I prefer this one to Cymbalta due to lack of negative ongoing side effects I had with that.

Good luck!

Update- This weekend will wrap up week 2 for me. I do agree with taking it with food, some mornings being too busy to eat I got VERY nauseous! I have noticed more energy & less overall body pain, but my back still hurts very bad ( I guess from my accident ). I wouldn't expect to find relief from Savella for that, just makes it harder to know the Savella is really doing it's job. I would recommend to anyone with fibro though. Lyrica was really nasty & did not help at all.

Happy to hear you all have had good results. I couldn't take savella, cymbalta or lyrica. The side effects were too horrific for me.

I have been taking savella for a while and it was amazing how good I felt! I did things I hadn't done in 3 years! then winter came...hasn't been so good. It also has an appetite suppresent in it. I have lost about 15 lbs. Every little bit helps!

I did not have a good experience with Savella. It started out nicely - increased alertness, energy) but that soon faded and I was back to square one except I had the added discomfort of the Savella side effects - flushing, insomnia, nausea). Oh, and if I even smelled alcohol, I would turn bright red and felt sunburned. Didn't mix well!
I stopped taking Savella and realized it wasn't really helping my pain at all.
Best of luch to you!!