Deep Vein Thrombosis (DVT) Support Group

Deep-vein thrombosis, also known as deep-venous thrombosis or DVT, is the formation of a blood clot ("thrombus") in a deep vein. It can be caused by something preventing blood from circulating or clotting normally. Join the support group if you are coping with DVT and find others who are going through the same challenges.

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nycjane 03/15/2013

Hi all - Unbelievably I just passed the 6 month mark from my clot. I am seeing the hematologist next week and hope for a good report. In the meantime though I have a situation. I may have mentioned previously that I also have rheumatoid arthritis. I am on a monthly infusion and am generally well controlled. Until the last 4 weeks.....I had pain in the joints of one hand and wrist and have been toughing it out till yesterday when it went after the other hand too (boo...hiss). My understanding was that I cannot take nsaids. I reached out to my rheumatologist and she said I cannot take the one I used to take, but I can take Celebrex. She prescribed it for me. I took one this afternoon and along with a Tramadol, it is helping (yay!).

But worrier that I am, I am worried. Has anyone taken Celebrex or nsaids while on (or off) warfarin. I am still on it, but am hoping to escape it's evil grasp next week. Naturally I will ask the hematologist about this but wondering if any of you have had this expereince?

Thanks....Happy Friday!
Jane

TossNTurn 03/16/2013

I haven't done this personally, but why don't you call your pharmacist and talk to them? They can give you the ins and outs of this kind of combination and let you know what to keep an eye out for. I know people have to adapt, depending on what their other issues are ... maybe it is something you can do, just be informed.

jan11965 03/17/2013

It can increase anticoagulation when taken with coumadin, so the recommendation is to closely monitor you to see how it affects you.

http://www.fda.gov/Drugs/ResourcesForYou/Consumers/QuestionsAnswers/ucm072436.htm

Brooklin 03/17/2013

I was told only to take Tylenol for pain while on Warfarin.
But, a few weeks ago my upper arm and shoulder started to hurt. The pain became almost unbearable. I iced it, I was taking non-aspirin all day long and I could not sleep. I finally called my internist and told her that I desperately needed some pain meds and that Tylenol was just not doing it for me. She called in a prescription for Tylenol 3 which is Tylenol with Codeine. I took two before bed and although the pain does not go away completely, I am able to sleep a bit bitter.
Long story short, I have a history of shoulder pain. I am 64 years old and I also have osteoporosis. I had a frozen shoulder 7 years ago which came after breaking my wrist in 4 places. Occasionally pain flares up and it's nice to know that there are other pain meds out there that I can take in addition to just plain old Tylenol.
I only take the Tylenol 3 at bedroom and use the regular Tylenol during the day. It seems to be working and my shoulder and arm are feeling a bit better.

rmb 03/18/2013

Celebrex is different from the NSAIDs that can cause GI bleeds because Celebrex binds to one specific enzyme that isn't responsible for the GI bleeds, while other NSAIDs bind to several enzymes, one of which is directly responsible for the GI bleeds. A friend of mine from my ulcerative colitis /Crohns group just shared that with me.

So from bleed standpoint, it's a better option than other NSAIDs, it sounds like. Still may mess with your INR but hell, what doesn't.

deleted_user 03/18/2013

Watch your INR really carefully while taking Celebrex. I was on it for arthritis and had blood vessels in my eyes burst. It seems to change the makeup of the platelets so anything can happen. I was instructed to take an antireflux medication with it to help avoid a gi bleed. I now use Voltaran gel when I need extra pain relief. It is a life saver! Ask your rheumatologist for it.

nycjane 03/19/2013

Thank you. I've only taken a handful, but what a nifty little drug it is. Really helped me. I have my 6 month follow up with the hematologist on Thursday. Am working on my list of questions, Celebrex included.

RetiredNavy02 03/20/2013

nycjane,

Read the pain management portion of this patient article:

http://patientblog.clotconnect.org/2011/07/21/dvt-long-term-damage-post-thrombotic-syndrome/

Hope that answers your question? Even though the article pertains to post thrombotic syndrome rather then arthritis,
Celebrex is listed as one of the pain management medications that can be used.

R/Tom

nycjane 03/21/2013

I saw my hematologist today and not only did she say it was fine to use, she said it could actually be helpful. I was very happy with that :)

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