Chronic Pain Support Group

Physicians and professionalsdefine pain as chronic if it lasts longer than three to six months and is persistent. It's distinct from acute pain that is a direct result of injury or trauma. This support group is dedicated to those suffering from chronic pain. Discuss treatments that have worked for you, find advice for your specific experience, and find support. You're not...

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Brain & Nervous System
/ Chronic Pain Support Group

nsaids and SSRI's

Community Leaderbobinmaine
bobinmaine
For those of you on antidepressants and nsaids for chronic pain.

My Pristiq wasn't working so I went to see my doctor about changing my medication or increasing it. While sitting in the waiting room I read an article in Arthritis magazine about a new study which showed nsaid pain killers such as ibprofen, naproxen....there are many others I cant think of at the moment but anyway, they interfere with ssri antidepressants ability to do their job. SSRI antidepressants are like Effexor, Pristiq, Zoloft, Paxil, Lexapro, Cymbalta, to name a few.

Needless to say, I cut back on my ibprofen when I was feeling down in the dumps.

Just thought you guys would like to know.

God Bless
Dixe4me
Dixe4me
That is a very good thing to know. Thanks.
debsue123
debsue123
I take cymbalta and a lot of advil and it still works for me but I take it for depression not pain relief so that is good to know. Maybe that's why I still hurt so much when I am taking them together. Thanks.
deleted_user
deleted_user
That is very interesting I am on Paxil and the doctor tells me to take ibuprofen four times a day no wonder I am sometimes in the dumps thanks for the info I am going to ask and maybe change things up a bit to see if it helps. Every bit counts right.
deleted_user
deleted_user
There are so many meds that interact out there. Thanks for the news. I am on an SSRI as well. I don't take NSAIDS very often but will defitnitely think before I take them.
Sandy
Community Leaderbobinmaine
bobinmaine
Its nice knowing I can help a few people just with a little information exchange.

I hope you all have less pain and can live a happier life. I know it's a tall order but it's something I pray for almost every day

God Bless
deleted_user
deleted_user
thank you for this information. I'm on Cymbalta for depression and pain. She also just put me on NSAID but it was just upsetting my stomach. But I take ibprophen alot. Good info thank you
deleted_user
deleted_user
Wonder what other interactions we don't know about?
gr8ful2b
gr8ful2b
Cymbalta, Effexor and Pristiq are SNRI's. That's a different classification. Just sayin'. Not sure if these are impacted by NSAID's or not but I've not noticed a difference. Thanks for the heads up. Now I'm off to check the PDR, lol.
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