Chronic Fatigue Syndrome Support Group
Chronic Fatigue Syndrome (ME/CFS) describes a sense of exhaustion and post-exertion malaise, even when you have gotten enough rest and sleep. The disease is characterized by six months of incapacitating fatigue experienced as profound exhaustion and extremely poor stamina, and problems with concentration and short-term memory. The cause is unknown, but it is a...
"Taken together, our data demonstrates that the significant decrease in deformability of RBCs from ME/CFS patients may have origins in oxidative stress, and suggests that altered microvascular perfusion can be a possible cause for ME/CFS symptoms. Our data also suggests that RBC deformability may serve as a potential biomarker for ME/CFS, albeit further studies are necessary for non-specific classification of the disease."
When I was in India, a very long time ago..struggling to hold up every day, an Ayurvedic practioner said that I did not have enough blood in my body and my weakness was all to do with my blood. However all the regular blood testing etc back here in Australia , reported as normal. I did have raised white blood cells always though. Cheers Di
https://iai.asm.org/content/82/6/2532
The important implications of RBC deformability in the pathogenesis of malaria have been extensively discussed (8–13). A significant decrease in RBC deformability arising from Plasmodium falciparum invasion was observed in vitro with different measurement techniques, including optical tweezers (9), micropipette aspiration (13), RBC membrane fluctuations (i.e., diffraction phase microscopy) (12), and probing of cells under flow (i.e., microfluidic flow cytometry) (10). Such parasitization of RBCs has been shown to increase their stiffness manyfold, with their elimination by mechanical filtration expected to compromise their microcirculation (8).