Sorry to hear it upsets your stomach! How did it go before when you were going off the Effexor and starting the Trintellix and you said you had stomach issues from that?

If this is a new stomach issue, then I would let your psychiatrist know about the side effects. Good luck!

I was on both Effexor and Zoloft (not together) and was also put on Wellbutrin to counter some of the side effects. Im now on celexia and am maxed out on wellbutrin (24h time release). I go into seizure risk if my wellbutrin dose goes any higher. Talk to your doctor about Wellbutrin. I hope it helps. 6 weeks is about the time it takes any SSRI to take effect, but jumping 75mg in 3 weeks seems a little aggressive. Good luck as well

I was up to 100 for a couple weeks. I was feeling so jacked up. So dropped to 75. Small improvements but still felt like too much. Last night I took 50. Will try that for awhile see if it levels.
I am waiting to see a psych, just working with my gp at the moment

It does take some time for these types of drugs (SSRI's) to fully work properly. Try your best to be patient and try to take this new change of meds one day at a time. I know it's difficult to keep trying different meds, but hang in there. Don't think ahead, or worry too much about *what if I have side effects forever* because the side effects should get much better after about 6-8 weeks, hopefully sooner than that.

Also, PLEASE consult your doctor before changing the doses around, even if you're changing it for one day. You could call his office and leave a message, even on weekends. It is not a good idea to "make your own dosing" if you know what I mean. These drugs are not meant to be taken "as needed". They are meant to be taken at a steady dose, and on a daily basis, according to what your doctor has prescribed. You can always call him and ask if you could take less, more, etc. You don't have to wait for your next appointment to ask him questions about the side effects.

Again, please check with your doctor (and hopefully your psychiatrist soon) about the doses you are taking and do what the doctor says. Good luck.

I had consulted him about going from 100 to 75. I left a message for him but he never called. The pharmacist actually suggested it as my diarrhea was so incredibly bad

How are you doing on it now? I know that it can be a day to day thing as far as how it makes you feel. Hope you are feeling better!

It really is just day to day. Yesterday was good. I had been off on holidays for a week which gave me way to much time to worry and fret. But yesterday I had an appetite again and a good day at work. Hoping this is the start of some peace and leveling

There is genetic testing available to find out which medication is the best choice for your body. Some medications are metabolized too fast or two slow depending on your system. It was very helpful for me to avoid side effects.

I know when I take my Zoloft on an empty stomach I feel really sick and very nauseous. I'm on 100 MG. I haven't had any problems since I started eating before I took the medicine.