I get those symptoms with any bio I have used. The orencia gives me sinus headaches too, but they go away in a couple of days.
I get infusions, I love orencia. Took over 6 months for it to kick in, but once it started, it was great.
I still get flares, but not as bad and not as often. Some months I'm on top of the world, then I get a month I feel the infusion was only water. But it's still the best one so far for me.
I took a few bios that were shots, you do feel poopy the next day, very tired. Even the infusion makes you tired.

Good luck, remember orencia is the slowest bio, it takes longer to kick in.

Lin

I get headaches from orencia sometimes
other ones I've used (humira, enbrel, remicade, orencia infusions) gave me more flu-like symptoms

I found my side effects have decreased over time (been on Orencia for about 18 months, first year infusions, then switched to injectibles)

I just had my first Orencia injection on Monday and I did get a lil headache. I hope it works for me.

Thanks ladies! I am hoping this one will work for me too. The biologics I have tried are Humira, Enbrel and Arava which didn't really help at all. But I will say, this will be the last one I try. Its just too scary thinking about the poisons I am putting into my body to only wish that it will somehow work. I am really glad I found the site.

Have a blessed day!

I was on Orencia for two years until it stopped working for me. It worked well while I was on it, but after about a year of being on Orencia I did notice that I had a headache after receiving the medication. I suffer from migraines, but this headache was different and would last for much of the afternoon that i received the Orencia. I also had some vision changes after the infusion. I am Plaqunil as well so my Rheumatologist had me hold the Plaquenil dose the night before and the morning of taking the Orencia. I would then have my treatments in the afternoon because I could not go to work after the treatments because of the eyesight issues afterwards. I hope Orencia does well for you.

Sometimes I get a slight headache the next day from Enbrel. I do my shot on Tuesday night so I will feel good by the weekend. Don't give up trying. None of us like taking these medicines but if you don't do anything the RA itself will destroy your body also. I had to finally accept that also. At least the meds give me a fighting chance against deformed joints.

i had 2 infusions of orencia (really, 1 and a half). after the first, i had one of the worst headaches of my life, and i get really bad migraines. during the second, i not only had a headache, but i got itchy and had a bit of trouble breathing, so it was concluded i was allergic - they stopped the infusion and pumped me full of steroids and i was fine. still had the killer headache for a day, though. i heard from a bunch of people after that that the headache is a pretty common side effect from orencia.

I definitely ended up with a migraine (which I have suffered from since I was young) yesterday and throughout the day felt really bad with pretty bad pain in my legs. Today is not so bad, so I will probably try it again next week, hoping it might have been a fluke. :-) "If at first you don't suceed, try, try again".

3 years on Orencia in medically indiced remission and no headaches. . I would recommend trying again after sinus infection is gone. The headache is likely from the sinus infection.

I have been on Orencia for 9 months. It has been wonderful for me. No side effects at all. I have seen that other people can have head ache and sinus issues. Keep in mind that at this time of the year there is also a flu going round that causes sinus infections so it could be something besides the Orencia. Don't get discouraged this stuff is the best thing I have found so far. It does take a little time to kick in. But as far as side effects go Ornecia seems to be the mildest. Good luck I hope this works well for you!
hugs,
Jan

Thanks Jan. I am hoping the Orencia will work too. I am just a little leary of trying anything else if this one fails too. The side effects subsided about 24 hours after my injection. I will say the Orencia shot does not hurts at all. When the medicine from the Humira auto injector would go in it would burn like fire, but the Orencia med does not. Woohoo!!! Have a good evening.

i have had the headaches, and the tiredness. some flu like symptoms. only on the orencia x 1 month (4 injections). I was thinking that the headache was related to work. Do notice that I seem to be in a small flare--achy ikn the ankles, feet wrists and fingers. shoulder somewhat sore. But it is significantly less than when I was on the humira, or embral.