Pulmonary Embolism Support Group
By far the most common form of pulmonary embolism is a thromboembolism, which occurs when a blood clot, generally a venous thrombus, becomes dislodged from its site of formation and embolizes to the arterial blood supply of one of the lungs. Symptoms may include difficulty breathing, pain during breathing, and more rarely circulatory instability and death.
http://fvleiden.org/ask/83.html
R/
Tom
The bridging you're doing is very similar to what I do when I have a colonoscopy.
3 days pre-op allows Warfarin's effective half-life to pass twice, taking you down to about 1/4 its usual effect. 4 days makes it negligible. Stopping Lovenox 1 day pre-op allows you to clot should you get scraped or poked by the colonoscope. Starting Warfarin the day of the procedure allows it to begin taking effect, but only slowly, while no Lovenox that day continues to allow scrapes or pokes to clot.
You would have a one-day window Monday to form unwanted clots. The risk of forming something life-threatening in one day is extremely low compared to any potential bleeding risk of the procedure.
Lovenox on Tuesday is important for two reasons, One is to arrest anything, however small, that may form Monday. The second is that Warfarin stops the liver's production of many proteins, some of which have short half-lives and actually prevent clots, which in turn requires the use of Lovenox to maintain anticoagulation. It takes two or three days for Warfarin's effect to become skewed between clotting and dissolving factors in favor of dissolving.
http://cmbi.bjmu.edu.cn/uptodate/vascular%20medicine/Miscellaneous/Clinical%20use%20of%20warfarin.htm
Now, for other types of surgery where a epidural may be used, Lovenox may be discontinued earlier then what the charts states but since that is not the case with colonoscopies I will not discuss further.
As yes RMB is correct the chart is for physicians but I find it a good reference point in cases where patients ask what to expect when undergoing a certain procedure.
Regards,
Tom