Everything I have read states to stay away from grapefruit. I know, love grapefruit. I have given up several foods that I really like to get my INR stable.

Grapefruit can really mess with a lot of meds. Reactions don't happen to everyone, but when they do they're pretty severe. If it were me I wouldn't mess with it. Just my opinion though!

I just checked the clinical pharmacology website, and Grapefruit is not listed as having severe adverse interactions with warfarin, and says there are no concrete studies to indicate any interaction. It cited a study of 10 people on warfarin who drank 8oz of grapefruit juice 3x/day with no change in INR. In one instance a patient drinking 1.5 LITERS of grapefruit juice/day for 10 days had a significant increase, but I can't imagine anyome drinking that much grapefruit juice, with or without warfarin!

I drank grapefruit juice in spurts while on warfarin with no problems. I did have to stop drinking after I started another medication, but I had no problems with warfarin. The juice mist often mentioned as a possible problem with warfarin is actually cranberry juice, but that has been pretty much debunked, and I also drank that while on warfarin with no adverse effects. Livin' on the edge, post-PE style, ha!

I've also drunk grapefruit juice (and eaten grapefruit) while on warfarin with no issues at all. I had to stop it because, like ShilosMommy, it interfered with another med I started taking. I've never heard of an interaction with warfarin when it comes to grapefuit...although I have heard of the cranberry one.

IMHO, if you're having some every day, there's no reason you can't have it with warfarin. If it causes your numbers to go up, your dose can just be adjusted down for the remainder of the time you're on it.

If you're really concerned, check in with your pharmacist as well and ask what they know.

Thank you!!!! I appreciate all your advice. I'm going to put a fresh Florida grapefruit in my juicer and have a glass :-) I have a box of them from a school fundraiser.

Grapefruit has a mild interaction with Xarelto but not Coumadin.

There are a lot of foods and drinks that may affect INR for coumadin/warfarin users, however, most specialist will concur that as long as these foods/drinks are within moderation and part of the daily diet your INR will adjust accordingly. There are patients however that may find that their INR just will not remain stable no matter what and may need to either eliminate all foods with vitamin K or stop drinking cranberry juice or switch to one of the new oral anticoagulant that is not affected by foods/drinks (other than possibly grapefruit which physician believe does not adversely affect how Xarelto work but may decrease it's effectiveness to some degree).