Hi, although my insulin levels aren't high I was prescribed Met to help get pregnant. I never conceived on Met alone, it always worked (for me) in conjunction with clomid. Once getting pregnant I then stay on Met through 16 weeks because many doctors feel that it lowers the risk of miscarriage in women with PCOS. My first child is a little girl that is now 1 year old and I'm currently in the 10th week of my second pregnancy with my second.

As far as side effects. It can defintiely contribute to mood swings, but now that I know that I do a pretty good job keeping it in check (with a few wayward moments during pregnancy :)). I have the stomach/GI issues, but they do get better with time. In fact the Met gives me a general feeling of 'not being myself', but you get used to it in time and it helps to focus on the end goal.

Good luck!

Thank you for responding!
Congratulations on your pregnancy...I pray that it is a healthy and successful one. My doctor knows that I want to continue to conceive, but since the miscarriage she thinks it's a good idea to put me on birth control for three months then try clomid. Before the metformin I think that I was a little more erratic....but then again I haven't been on it more than a week so we will see. I take them before bedtime and when I wake up I feel nauseous. I'm nowhere near as nauseous as I was before all of this.

I do feel better that I was finally diagnosed because finally I know what's wrong with me...I guess I could deal with the nausea since it's nowhere near as bad without metformin.

I also just sarted taking metformin . . . . good luck with everything

Thank you and good luck to you too!!

I started on Met in Sept 2009 due to PCOS,my doc told me it would help me ovulate and after about 8mths I got pregnant so it does help,in the beginning I had GI problems for about 2 wks.During my pregnancy I continued to take it.I gave birth at only 18wks and lost my baby but it had nothing to do with the medicine.
Good luck and keep me posted

Thank you for posting! I'm so sorry about your loss. I unfortunately miscarried too but I didn't know that I had pcos at the time. On Friday I just increased my dosage to 2 pills a day and was sick and vomiting all day yesterday. Today I feel strong nausea and will spend the rest of today in the bed. I sure hope that I don't go through this the rest of the week.

I don't know if you are already taking the ER or extended release version of Metformin, but I would recommend asking your doctor about it if you are not already on it. It can really help with those nasty GI issues!!

I take 2000mg Metformin ER since July of this year. I started at 1000mg and the dose has been increased by my RE (reproductive endocrinologist).

I found out I had PCOS in July of this year and just took my first month of Clomid (50mg) but unfortunately still didn't ovulate :( but I'm hoping that my RE will up my Clomid dose to 100 mg and hopefully that will do the trick....I hope. :)

Good luck to you!! I have to keep reminding myself that I will beat infertility, it will not beat me!!

ali: Actually I am taking the Glucophage XR. I was thinking that the extended release was the issue, but I don't know. I'm eating more carbs to try to fight this nausea. It seems to be working so far.