Polycystic Kidney Disease (PKD) Support Group
Polycystic kidney disease (PKD) is a progressive, genetic disorder of the kidneys. It occurs in humans and other organisms. PKD is characterised by the presence of multiple cysts (polycystic) in both kidneys. The disease can also damage the liver, pancreas and rarely the heart and brain.
How do you know that one kidney has an GFR of 10 and the other of 30? Serum creatinine (from a blood test) can only tell you overall kidney function. If you were to find that one kidney is at 10 and the other at 30, I would have thought that overall function would be an average of the two, ie 20 (ish) but this may be wrong. I'm sure you don't add the two together to give 40 though. Whatever your GFR, there's no knowing how long you have until renal failure. Function may stabilise for a long time, decline slowly or decline quickly. It's difficult to predict this with any accuracy. Don't forget that creatinine does fluctuate, so you can't read too much into any one measurement.
Life expectancy of a transplanted kidney depends on many factors, but I understand that it can be up to 20 years. Again, it's the how long is a piece of string question.
I'm sure others in the group will be able to offer more knowledgeable comments.
Take care,
Chewitt
as to creatinine, a jump from 3.6 to 3.8 is pretty meaningless because many things, including how much water you drink, can cause these small changes.
how long IS a piece of string? I like that and it answers both your questions. we are all different and how you take care of yourself is a big part of the answer.
My neph asked me to get a test done called DTPA, this is some nucleur medicine test to evaluate functioning of both kidneys and provides individual GFRs.
I looked up the dpta test (renogram) and it seems that it measures kidney function, excretion of urine and blood supply. It enables determination of how much each kidney contributes to total function. This gives some information:
http://www.insideradiology.com.au/pages/view.php?T_id=43#.Ul4-Jcu9KK0
In the light of this information, it may be that your total kidney function or Grfr is indeed 40. I think you need to ask your consultant to clarify this.
Chewitt
take care