Schells, What is your Neuro basing this decision on? From my studies this drug is still be used as a neuro protector by most Neurologists. Is there some new studies that your doctor knows about?

I have not gone on any drugs yet, but my doctor has recommended I go on either Azilect or Selegiline for the possible Neuro protector effects. He did say it was theory, and not totally proven, but the studies were good. So what is your doctor reading that makes him or her think differently?

I had a Neuro nurse who I talked to about participating in a study recently basically say the same thing your doctor just said. i guess i need to question her and my Neuro further.

Have you had any side effects from going off the Azilect?

Hi Schells,


Did you have any problems with Azilect?

I started taking 1mg a couple of months ago, as I was told it was a neuro protector, my own neorologist said if he ever got PD that's what he'd take. I've had no side effects and although I don't know whether it's doing any good I just assumed it wasn't doing any harm. Why did you want to quit it and why doesn't your neuro think it's worth a chance?

I hope you are feeling better and the sleep issues are resolving.

Take care

Julie

Julie I trusted azilect for about 3 years believing it was helping progression and maybe it is. Neuros have conflicting opinions. I just want to sleep and stop the crazy dreams. May not even be the azilect but I think I should have tapered off instead of quitting cold turkey.

Just when you think you have this disease figured out....well...

Have appts coming up so maybe I will know more then-hope you are feeling good and your day is great!

I have been on Azilect for 7 months now. I have never had any side effects and I sleep well. I keep a set bedtime and a fixed ready-for-bed routine.
I am still in early stages of PD. I saw some improvements early on, but in the last couple of months I am slowly regressing again. The only other thing I take is 2000 units of Vit. D. I was rather deficient when diagnosed. My last test was back to the low end of normal.
Of course there is no way to tell where you would have been without the Azilect, but I agree that it is worth the chance.

My doc advised eliminating it from the med regime. It has not demonstrated evidence of PD progression sufficiently enough to warrant the expense and risk of this drug. I'm down to 0.5 mg for two weeks, then to zero after that.

There is evidence starting to show that DBS is in itself neuro-protective. But its too early to tell just yet.

C

I've been taking 1 mg for about 7 years. I did have some minor side effects when I first took azilect, but this pill is all I take for PD. I have no idea if it is helping, or not. There should be some findings, by now, as to if azilect works, or not. Please let me know if anyone hears of any new results on this subject.

I tapered off Azilect for a couple of weeks, and discovered i feel like absolute hell without it. So I'm titrating up to 1 mg per day again.

C

I feel like the fly on the wall. Dx'd 18 mos ago and been on Azilect ever since. My neurodoc explained that Az *seems* to slow down progression of PD, but that jury is still out. It is the only PD med I take. Can't say I notice anything good or bad, even when I skip a day. Many times I have wondered if I should be taking M&M's instead. It'd be cheaper, the chocolate would be more rewarding, and I wouldn't have to limit myself to one a day.

Beekeeper

I tried Azelect several times and got the same side effects each time. My doc also told me it would protect the cells that are still good so I kept giving it a try. It didn't work out for me and each time he told me to wean off it and not cold turkey it.... Hope you're doing ok!!!
paula

I have been on 1mg of Azilect for about a year- not impressed . It seemed to help stiffness early on but the benefits were short lived... I also don't like that it has deadly consequences if you mix it with the wrong medication- and a lot of foods react badly to it (fava beans, most cheese, and many pickled foods) good riddance- I have been reading about the good results people have been getting with a supplement NAC. and of course magnesium and D3 ....... I would like to try mucuna pruriens...anybody try that?

I have now been on Azilect for 5 and a half years. I still have no evidence that it does anything. I still take it on the possibility that it protects. I recently asked my doctor about the generic version available across the border. Potential savings of $1000 us dollars a year is attractive.

I have been on Azilect for nearly 10 years, and it has no t seemed to cause any untoward effects. And my Parkinsons has been relatively tame from what I read from others. I would love to get off anthing not absolutely necessary, but wonder why I don't have worse Parkinsons than others affected a shorter time. Mine IS progressing, at least one field of evaluation puts me at a 3, but most others, a 2 on the scale of 1-4. Still I'd like to have a trial off just to see if it might help me feel less flat, less apethetic.

I have been on azilect nearly a year now and my tremors started to worsen around June time,never thought it could be azilect making them worse so I tried more exercise,magnesium,healthy diet,vitamin d supplements,massage twice a week,compression sock for the tremors.no joy so at the beginning of this week as the pains in my shaking leg got worse and brought me to tears and sadness I stopped taking azilect,I'm still on madapar and sinemet,as the weeks gone on I have had more on time than off time a bit more each day.ive not spoken to neuro yet about this yet,hope going cold turkey is fine

I was on Azilect for five years with a tyramine free diet no side effects. New Neurologist took me off it saying the trials had not shown good results
I had been coping well with Stalevo x 5 times a day until an extremely stressful yr due to death threats by my daughter's estranged husband on my life my daughter's life & all our grandchildren
my neuro put me back on Azilect again along with madopar rapid, sinemet CR & stalevo x5 daily doses
After 2 months of 1 mg daily dose of azelect
I started having severer side effects
Daytime falling asleep anytime anywhere, a hacking cough, nitely dry mouth, throat & nose constantly disturbing my sleeping, lack of appetite & hallucinations
When I tried to contact my neuro a week later I received a phone call saying no one else had complained
In desperation I rang my pharmacist about stopping my single dose of Azilect she told me to cut the 1 mg in half for a week & then a 1/4 of a tablet for another week
Feeling all on my own ,I am ceasing all Meds except 5 x Stalevo daily