i tried cymbalta for about 9 months and it did not work for me. my neuropathy is past the poin of cymbalta helping. i hope it works for you, give it a chance and monitor you pain levels and wait and see. good luck and feel better.

Fahmah, Your diagnosis is exactly like my husbands, autonomic neuropathy and Addisons. How do you cope with it mentally? Depression has over come him.

Keep taking it in the morning. It it supposed to help the fatigue. You might need something else for the pain. Lyrica didn't work for me, it only made me gain weight and feel confused (this while I was running a machine). I never could take it but once a day because of the risk of getting hurt. Neurontin was the best for pain for me until it quit working.

Oh gosh I hope neurontin , does not stop working for me. I take it along with Cymbalta . I also take Alpha Lipolic Acid. I take mentanx as well. The combination of all of it seems to help. I take the Cymbalta in the morning. Take care!

Cymbalta is a drug that has to build up it's levels gradually and so it probably doesn't matter when you take it. I take Neurontin and I have reached the dose that is the maximum efficacy - 2700mg a day. The pain clinic tells me that although I could take a max of 3600mg it has been shown that it doesn't work any better at that high dose. They tried me on Cymbalta but it didn't work. My friend takes it for severe depression - it has probably saved her life!

Thanks folks.
I have been on Cymbalata over a year. I have gained weight since taking Lyrica at first the docs didn't believe me that Lyrica was causing the weight gain. I do find that if I take Tramadol early in the evening the pain is less- like I am getting a jump on it.

I have found that wearing extra heavy support knee highs from sears helps..

I use oral Lidocaine on my feet before I go and do a lot of walking. (Some of that pain is from the nerve from my big toe runs on top of a plate on the top of my foot.)

I'm taking Cymbalta in the morning and neurotin 3Xa day. I don't know if the cymbalta helps but since I suffer from depression, too I keep taking it. I'm afraid the neurotin is not working as well as it did. I'm new to this discussion group. Thanks for being here.

I started Cymbalta in June 2011. I found that it made me terribly sleepy during the day after I reached the 60mg dose. I switched to taking it at night instead of morning to see if I would feel better during the day. So far it doesn't really seem to be doing anything for nerve pain. I do get a little more sleep at night because it makes me very sleepy.

I also take Lyrica 3x/day. It also makes me sleepy too. I am not taking the maximum dose. All it does is take the edge off of the pain a little bit. That's better than nothing! I tried neurontin but it didn't work for me. I couldn't get past 200mg per day. Have you tried Lyrica yet?

I hope you can figure out what works best for you and get some relief:-)