I've taken it for about 1 1/2 years. It has helped me so much. I didn't have much trouble adjusting to it. I didn't like the taste so I would drink it quickly. That was not a good idea.
I feel so much better but still get tired in the evening. I wish I didn't have to take it but I'm thankful that I can. Good luck!

I was diagnosed about 4 years ago, I started out with Xyrem, but I was still struggling to stay awake during the day, so I was prescribed Provigil (Nuvigil's generic) to keep me awake during the day. It works better for me than the Xyrem did, plus I don't have to wake up in the middle of the night to take that second dose.

I have only been on xyrem for a couple of weeks, but I am finding it more difficult to go to sleep, my rls seems loads worse and I am waking lots more in the night. by the morning I am absolutely exhausted, and at the moment I am only on 4.5 a night. I am not sure that I can continue like this!

I have been on Xyrem for about a 3 weeks now and I am at a very low dose due to a reaction I had with it the first time I was put on it. I am not sure if it is helping. I am also on Provigil 2x a day and I struggle heavily with staying awake. The scariest is when I'm drinking to and from work. I am at a standstill with it all. My husband does not understand this condition and does not support me as I need him too. I have tried to have him read about it, watch videos about it and he just thinks I have a hard time sleeping at night. I feel very alone and I am becoming very depressed. I do not want to be like this anymore.