Myasthenia Gravis Support Group

Myasthenia gravis (MG) is a neuromuscular disease leading to fluctuating muscle weakness and fatiguability. The hallmark of myasthenia gravis is muscle weakness that increases during periods of activity and improves after periods of rest. Although myasthenia gravis may affect any voluntary muscle, muscles that control eye and eyelid movement, facial expression, and...

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Mestinon side effects

Speechie
Speechie

Some new members have asked about side effects of mestinon so I'm posting this for them. I have generalized myasthenia with fluctuating weakness in legs, breathing, eyes and voice/speech. When I started taking mestinon, I had all the side effects to varying degrees. These days, I have the excessive saliva, cramps (in legs and feet) and sweating ones. The sweating is a daily thing but the others come and go. You can take too much or too little mestinon. Too much can mimic a crisis so be careful. Been there, done that. I've had MG a long time and vary my dosage daily sometimes taking less or more than what bottle says (with my doc's okay). At end of month, it all evens out as I've never run out before refill date.  I think regardless of prescription, you have to find the "sweet spot" for your own symptoms and how much discomfort you can put up with ( if you have any) for your muscles to move. These are the most common side effects of mestinon: Excessive Saliva, Excessive Sweating, Nausea, Vomiting , Diarrhea and Cramps. 

fihghter
fihghter
you have given very good description of effects from mestidone, the only thing i want to had, lets not forget that as we are all different in how drug react to us, you will have to learn to control what is going on with your body and your dayli life. i know some times it hard, but is realy achievable, please use commun send, logic, that will help all ,of you as it has done with me, his is the reason that for the last 5years i am at the minimum dose of 30mg.dayli, i am a generalized mg. assciated with other complications, but i was able to overcome all the goodies that come with mg. (i beleive??))

best of luck
Andre
Rhanson
Rhanson
Yes, mestinon can be pretty bad with its side effects, but I found that without it I couldn't do much of anything and with enough of it I could live somewhat OK. Eventually with prednisone I didn't need much mestinon.
I always carried extra shirts, antiperpirant, wet ones etc when I did something physical as I would get just ringing wet with sweat. And the night leg cramps were pretty thrilling too.
Good Luck
Russ