Myasthenia Gravis Support Group
Myasthenia gravis (MG) is a neuromuscular disease leading to fluctuating muscle weakness and fatiguability. The hallmark of myasthenia gravis is muscle weakness that increases during periods of activity and improves after periods of rest. Although myasthenia gravis may affect any voluntary muscle, muscles that control eye and eyelid movement, facial expression, and...
Am currently having IVIGs 3 concurrent days every other month. Two cycles completed. Also 20 mg Prednisdone and 540 mg mestinon every day.
The last two cycles I have experiened what my wife calls - aggrivated/irrational/argumentative - behavior at times.
I know that the Prednisdone can increase aggression and agitation but it appears that it is worse during IVIG.
Thoughts?
S
after reading your question there is no dought in my mine as i have been tru various series of ivg, that the ivg's hve nothibg to do with your mod changes..
this is due all about prednisone, , i am sure that you are taking predinisone for a certain time, so let me claear some points, i have been with predisone in various stages and allways as soon i go up more than 25mgs, dyli, i have mood changes, call it alterations of the prednosne
3 things will happen with large doses of prednisone
1) high blood pressure
2) high blood sugars
3) high collesterol
and the most important constant changes of mood, depending the dosage
i have gone tru all these stages, and even that i am a person very stable, i had dificulies with control of my moods, sometime,angryness prevail, ,irritabilty. and others, but never i experience down moods.
so my best advise to you speak with your neuro and endocrinogist, to reduce the dose down to 5mgs. dayly which i am most of the time that i have mg. 9 1/2 yrs.
prednisone is use to supress the inmune system, but it has better value in controling inflamtions and infections.
our body preoduce about 5 to 7 mgs. of cortisol dayly,, so this explanation should be an indication of what you should be takeing
best of luck
Andre
IVIG days start at 5:30 am. Out the door by 6:30am. 1 hour drive. In the chair plugged in by 9 am. Usually done by 1 pm and on my way home.
Will chalk up the mood/anger stuff to prednisdone. My PCP has prescribed Hydroxyzine to reduce some anxiety and help with sleep. I do not use it often but will use it the next IVIG.
My symptoms still seem to be progressing. Lately am experiencing some swallowing problems and aspiration issues on occasion.
The Neuro wants me to stay at 20mg prednisdone and IVIGs for a while yet.
Ain't life grand? :-D
Have had video swallow nothing showed up. EMG and nerve condition normal. Sky high acetylcholine antibodies Though. Spot on thymus that’s not thymoma and not growing but doc says caused the bad antibodies likely
I really do not know if what I am about to try to describe are actually MG symptioms as I am not quite 1 year into this thing.
Aspiration - Spit, food crumbs......Before MG I would rarely aspirate these days 2 to 4 times a day.
While swollowing it seems at times - Instead of the throat musces continuing to push down the food/drink, it seems like it just stops and/or slows down.
I hinted at 'problems' in the first year or so and even for me, they were fairly severe and worrying. Certainly, eating was difficult as was talking for anything over a minute or so. All I can say is that I came out the other end and now nearly twelve years on. life is good and there are no real concerns with MG.
Let's hope the same result for you.
Take care.
I am hopeful that this disease will bottom out sooner than later and I too can say that I do not have MG concerns. :-D
Talk to your doctor -- there are some meds that can be given to get you over the rough days afterwards.
Good Luck!
(I am on an extended two month vacation in Texas (from MN) and am not very often on the internet unless I go to a library).
Russ
Always nice to hear your voice.
S