The heat definintely makes us weak, and that is what leads to my hand shaking when my Mestinnon is wearing off. Why some muscle groups are more involved than others, I don't know. I notice mine most when trying to hold a heavy glass at the evening meal which occurs at the time my medication is due. I haven't had enough trouble to vary dosage timing, but that is something you might consider.

It is a good idea to do your most exertional activities at your peak dosage when your muscles are working at their best, that way unaffected muscles do not get overused and injured.

This is something to bring up with your doctor, but meanwhile you might try varying your activities with your medication. b.

I guess I am pretty lucky I work in a office setting on a computer designing for highways. I was going out surveying and since all of this that was a just a little much. The Mestinon is a good idea will make a note and ask my doctor when I go again. There is alot to know and understand about this disease and that is some of the battle.

I get shakiness in my legs and to a lesser extent my hands when I've pushed myself past my limits and then the Mestinon is wearing off. Beth's advice about matching activity to peak dosage is excellent. I've tried it and it helps.

I read a comment by a doctor with MG I'm trying to keep in mind. She suggested doing slightly less than you're capable of rather than pushing to your limits all the time, so that you have a reserve of energy. Like if you can climb 4 steps before resting just climb 3 then rest. Her approach does seem to reduce fatigue so if your shaking is possibly caused by overdoing it, you might try her way.

The heat is a nightmare. Several 100 degree days in a row here and now I see why MG is called "the ragdoll syndrome". I pushed the trash cart to the curb today and could barely swallow or climb the steps by the time I got back to my porch about a minute later.

Take care,
Rhonda

Agree, the shakiness in hands happens to me , and the heat is a killer...

I also get shaky hands. I work with a lot of papers and think people are going to think I'm nervous/anxious when my hands shake while holding a piece of paper or try to pick out a particular piece of paper in a stack. Have even commented that I am not nervous, just have something going on health wise.

I have heard that prednisone can be a culprit in hand shaking, although I had shaky hands before taking that drug.

Everything is more difficult in the heat! I am on the east coast and we are in a dramatic heat wave/thunderstorm situtation. Fortunately I did not lose power as many did from the storm. I will do anything to stay out of the heat - even if it means driving between stores in the same shopping center :-)

Sully

I thank you all for the information I am taking notes and hope to go to a new Doctor soon. It has been very hot here so that may explain some of it. This is one strange disease with even stranger medicine you never know what is going to happen next.

Daily arm shaking here, mostly through to mid morning with my tea. Sometimes too when I hold the phone so I've learned to slouch on my desk for support.
With the increase in temperature I find I need to increase my mestinon as well.
Larissa

I have leg shaking, but Its Not weakness. It probably a side affect of mestinon, But i have It when i feel hungry in the morning. So Im Just sharing some info. Good luck!