The cellcept could take a year or more to be effective if it does work. It may not either as the research on it is somewhat uncertain but most folk seem to have a long startup curve with it.

Prednisone at 60mg/day could take 6 months for maximum effect depending on your weight, although it should gradually begin to work earlier.

One reasonably clear discussion of the treatments and timelines is from this website.
http://www.australianprescriber.com/magazine/30/6/156/60/

The usual prescribed prednisone dose (after ramping up a few weeks to make sure you don't have an exacerbation with the start) is usually give as 1 mg/kg (your weight). So a 60mg would be standard for 60kg person (132 lbs)

I took 60mg (I weighed 100 kg) tapering up gradually from 20 and 6 months later was free of most MG symptoms and beginning to taper it back off. My doctor tapered me up somewhat slowly as she was worried I would get type 2 diabetes -- I didn't.

Good Luck and be patient

It took me a good couple of months and some increases of dosage to get where I wanted to be with Prednisone--I'd talk to your doctor about what his hopes are for you, but my neuro described Prednisone as a freight train--it's hard to get it rolling, and also hard to stop!

It took about 4 months to start noticing any affect of prednisone for me.

I remember feeling noticeably stronger at 6 weeks on prednisone.

Thank you for your responses!

Another question I have about these two meds is in regards to sweating....... I mean seriously sweating while on them. Since starting them, I sweat like crazy! Is this something that anyone can relate to? :)

Mestinon was terrible for making me sweat with even a little activity I took extra shirts along with me in the summer. When I got off it and just on prednisone it disappeared.

Good Luck

Mestinon will definitely make you sweat.

I am on 40MG Prednisone and 2500MG CellCept daily. Have been on CellCept for about three months. I am about 75% of baseline, and I got out of hospital due to a crises on arch 28,2015. I seem to be getting slowly stronger every week.

I'm not sure your Cellcept dosage is enough. Studies show it being effective @ 1500 mg and higher per day. Hopefully Cellcept works for you, because it is about the safest drug we have.

I would imagine the sweating is from the mestinon, considering you are taking it all day also.

Hang in there!

Call him. I delayed calling my doctor in February, and went into a crises. I a now on 40MG Prednisone, 2500MG CellCept, and 360MG of Mestinon daily. I had three 60MG doses of IVIG about a month ago.I am back to about 75% of baseline and improving slowly. I don't know how long you have been diagnosed, but it the condition usually gets worse after it gets better during the first couple of years.

I was on Cellcept for about a year and a half before I really started to stabilize. That is likely due to my weight and thyroid disease as both make metabolizing meds and food a much slower process. Prednisone started to really take hold after about 2 weeks for me. I think that was because I was pretty much on it all the time. Every time I got a sinus infection the doctor would give me antibiotics (that almost killed me) and a steroid dose pack. I usually ended up on that type of treatment no less than once per month. Every single time I'd dread stopping the prednisone because I felt so much better on it than when I was off of it.

Hang in there and give it some time but I will still call your neuro and make sure that you are progressing as your doctor intends you to.

Good luck!