Myasthenia Gravis Support Group
Myasthenia gravis (MG) is a neuromuscular disease leading to fluctuating muscle weakness and fatiguability. The hallmark of myasthenia gravis is muscle weakness that increases during periods of activity and improves after periods of rest. Although myasthenia gravis may affect any voluntary muscle, muscles that control eye and eyelid movement, facial expression, and...
I've been prescribed some .125% nitro glycerin ointment for a fissure, and the doctor was a little concerned about it's interaction with MG because it's supposed to relax the muscles in the area where it's applied but is also usually absorbed systemically. My neurologist - who's really good so I trust her - said that there shouldn't be a problem, but I was wondering if anyone else has some experience with this as I'd like a little extra assurance!
Carvedilol is described in medical reviews, as a med that must be used with caution - with MG'ers.
The Carvedilol doses were started low, at 6.25mg, twice a day. After a while, the dose was upped to 12.5mg, 2 x daily. Since I seemed to tolerate the Carvedilol, the doses were then 18.75mg. Then 25mg, where I am today.
I've been on this 25mg, 2 x daily - for many months now. In that same time frame, my MG symptoms have actually declined.
At the same time, my heart has been slowly mending itself (blockages). Carvedilol is helping.
True: Nitro-Ointment and Carvedilol are different meds, but both have the affect of relaxing muscle. In my case - it seems to be of decent benefit.
Wishing you the best!