I tried it -- but didn't take if very long. It worked, but as my need for mestinon varied with my activities I preferred to take extra before an activity and less when I wasn't active. The extended release felt to me like it was not flexible enough for my needs.

When I took it 2013, it was quite costly compared to my cost for regular mestinon and that probably influenced my opinion too.

Good Luck
Russ

Thank you so much for responding. I feel the same exact way guess neurologist and my primary are hoping will help with my breathing so I don't have to go back on prednisone.

Tams, I know it’s been a while since you posted this question but I thought I’d chime in. I take mestinon timespan 180mg in the morning along with 60mg regular mestinon. Then mestinon 60mg mid day and 90mg of timespan and 60mg regular in the evening. It’s been a huge help! No more of the horrible ups and downs I was having with just the regular mestinon. Definitely take it with a meal though!

Hello Tham64

all meds taken are trial and errors, mg being a funny disease to deal with,

when i contracted my mg, i was taken for a while the extented mestidone 180 mgs. per advise of my neuro a was taken 1 1/2 pill in the morning then noon, afternoon and evenining, as this was temporaru and every 2 weeks i was decreasing the amount by 60mgs daily.untill i reach the minimum in 8 months of 30mgs. dayli

i found that the hi amount where better taken in the morning and noon do to the dayli activities, afternoon and evening was taken much less, because the dayli activities generaly speaknig decreases as the day progreses.

also i found that my splitting a 180mgs, per consultation with the makers, was told, that if you split the pill, the extended potency become only regular (meaning 4 to 6 hs.)

but for me at that time served the purpose, if you are a person whom may have dificulties with mestidone, i suggest that you take in consideration the dayli extenous activities , and adjust accordingly.

some times we take for granted the simple things and become all despondent, but remenber we are the ones in charge of our disease and we are the ones whom have to trial and err, to find the proper dosage and control
i am just in remission the last 3 months of my worst relapse,and had to use lots of logic and commun sence, to be able to control the down spiral of my respiratory system shutting down

so to all do not feel despondant that we are int his togheter, and can take bits and pieces from each other experiences. to better understand what is going on

best of luck to all (fighter)

DarlinGin- Thank you for responding i wrote down your doses of medicine to bring up to my neurologist in oct for my 5 month check up. curious if maybe this is something i can try to help with all my ups and downs its starting to take a toll on me

fihghter- Thank you for responding it means a lot to be able to come on here and ask these questions.