No insight but i've been watching this med and it seemed vetr interesting to me. Has it been approved?

Dr. Orange wrote about it when she summarized the new oral meds comming out.

http://www.dailystrength.org/c/Multiple-Sclerosis-MS/forum/Treatments/12114239-oral-ms-medsso-many

2) Teriflunomide. In an ongoing study of 1,088 patients with relapsing-remitting MS, a single daily dose of 7 mg or 14 mg of teriflunomide was compared to placebo for 2 years. Both doses reduced the relapse rate by approximately 31%, compared with placebo. The risk of disability progression also was also significantly reduced by 30% in the 14-mg group.

I will be intersted in reading the replies and youre experience with it if you decide to go that way.

Last sentence about being intersted in this med was mine & not Dr. Orange.

It's in Phase III clinical trials.

http://clinicaltrials.gov/ct2/show/NCT00622700

This website says they are currently accepting patients 18 -55, alas, I'm too old...

The study my neuro is considering me for has 1500 patients from 28 countries. The patients included in this trial have to already be taking interferon 1b and have had at least one relapse in the last year.

You take interferon 1b in addition to 7mg, 14 mg Teriflunomide or placebo.

I was just wondering if anyone was on any of the earlier trials or has any information on this medication from personal use.

Still no experience with the med but it still sounds very interesting.

I'm just posting this because I feel like sharing the thought.

a few months ago I ran into a person who had been a part of the first tysabri trial before it was initially approved.

He told me he wished they would give the status of the risk factors and outcomes for the group of people that had been on tysabri the longest, during the original trial..

Stupid me. I had read about one woman's family that had filed a lawsuit against boigen after she died because on autopsy it was found she didn't have MS. She had been diagnosed with sensory symptoms and her mri never meet the McDonald Criteria for definite MS..so her family said that she was incorrectly allowed into a trial where the med eventually killed her for the treatment of a disease the woman didn't even have.

After that biogen required that all participant in their trials have definite MS as verified by MRI and the McDonald Diagnosing Criteria.

So he knew about the outcome of that person from the trial, it was public, and he had come into contact with one other person from the trial.

Stupidly i asked if he kept in contact with the other from the trial...like that had yearly re union meeting? Uh Duh!

I can understand for the trial to have objective results during the trial and afterwards, the participants have to be kept separate and not communicating with each other. like juries are not suppose to talk about the evidence in a trial until aftwards when they go into trial deliberation.

But its a shame that people in a trial are not given the names of the other people in the trial afterwards...

We almost need an organization to help people in trials find others in the trial like there is an organization to help adoptive kids t find their biological parents,

We need some type of organization like that--find other trial participants. Where every could register once they start a trial, over the internet ,so finding them is not so difficult after wards.

I went to a Research lecture about 2 wks ago sponsored by the MS Society. A female neuro gave us a lecture and I took notes. Now I am not on the drug BUT this is what my notes say about Teriflunomide:

it is oral, inhibits enzyme DHODH (whatever that is!), approved for rheumatoid arthritis so it has been on the market for >12 years. I has a real long 1/2 life and there is GI discomfort.

Try going on the rheumatoid arthritis site and see what they say about this drug since they have been using it for over 12 years.

BTW, the doctor giving this lecture is taking money from the Betaseron drug company. I am writing her a letter about that part which is what I don't like and also the fact that there are too many drugs coming on the market for treatment of progression and not a CURE.

Anyway, the drug sounds good if you don't have GI problems but ck with the arthritis site.

HUGS!!