It works but for me it puts me to sleep almost immediately. It works better than any sleeping med I have been on.

If I take it too soon, I will fall asleep in the chair (and I have never ever done that in my life before Zanaflex). So for me it is really a muscle relaxer for nighttime. But, of course, everyone is different and it might not do that to you. But be careful, it may put you to sleep and be ready. I would not drive and take it.

I have been taking tizadine for 6 mo. I checked with people here about it first. The general consensus is what ezone said. It can make you sleepy, so the two pills I take a day I space out, taking 1/2 in the morning, the other half in the afternoon, and a whole one when I wake up to pee in the middle of the night.
I have to admit, other than helping me sleep a bit better, it hasn't helped with the spasticity as much as my neurologist would have liked, so he has now added cannabis (so far I am not noticing a huge improvement, but I've only been using it for a little over a week!)

I have took tizanadine since I was diagnosed with MS which is a little over a year. It does help me but I have to take it at bedtime because it makes me so sleepy. It is 4 mg. I have tried taking half during the day but cannot because I am unable to lay down. I wish you the best.

How long does it seem to last? I take Baclofen at 10 pm but wake up from jerking around 2 or 3 and often after that the rest of the night and can't take it again until 6 am.

Gentle hugs, Linda

FYI, they are working on an extended release Baclofen pill. I am in a study for it right now. You take it once a day...after dinner and thats it. So far it seems to get me through the nights. Blessings to you.

My doc put me on keppra. It's kidney friendly, and it doesn't knock me out. It helps with spasms and tremors. I haven't taken zanaflex so I don't know how it works.