I noticed that I do have pain in my legs and ankles. I have always had back pain, and I know it is not from the MS because pack pain runs in my family. But, you should ask your doctor about it too. When I asked my Rebif nurse about it, all she told me is that exercise helps, but with pain in legs and ankles, you will have trouble exercising...so, maybe you should ask your doctor why and what will help. Good luck with everything, and I hope this helped!

Mine hurt 24/7 also

doc doing a mri on my lower spine to see how much is ms and how much is d disk diease.
they tell me the vice grip feeling is the ms and the dull ache is problem with the disks

My legs have been hurting for a year now, almost constantly. It isn't an acute/sharp pain, but more of a constant ache.

I started Aqua Therapy in January and that has helped a little, but it also turns out that I have a blockage of the artiery somewhere in my right leg which is causing the muscles to have to work without enough oxygen (which causes the right leg pain) and that my left leg is hurting because I've started to walk differently to compensate for the pain in the right.

All this is to say that while it could be your MS, it might now be. You should ask you regular doctor to take a look and see if there isn't something else going on. Your MS does make you prone to other things too.

My doctor did a spine mri too, he felt like i would have spinal lesions since i complained of my legs so much. The mri did not show any lesions, its all coming from brain lesions. Oh yeah, and my ankles hurt like crazy too and the bottom of my feet burn. Its crazy. Thanks for the replies.

My second attack ever occurred last August before I even had a diagnosis yet. My legs were affected during that attack, and ever since I have had aches in them. It isn't a constant thing...but it does seem to happen when I have over did it, or just when just plain tired.

Mine also ache alot of days. My doc gave me med to sleep at night b/c they ache so much i cant sleep. So far So good.

My legs hurt all the time too! And I'm always sooo tired! My MS has caused a few other problems too, though. I've got 2 new lesions on my brain, according to MRI. Guess that's what's causing it. It seems like it's hurt for so long, I kind of forget about it most of the time. It's starting to seem natural, like blinking your eyes and breathing. Thanks for posting this. I'm glad to find out I'm not alone. I thought it might be something else, too, causing the pain. :)

My Dr. perscribed Mirapex one at 5pm and one at bedtime they are 0.5 mg to help with leg pain it seems to be working

Anyone tried B12 spray OR injections for nerve pain??

My legs hurt 24/7 too, and yes I have the joy of fatigue... I've tried exercising it doesn't help me, the next day my legs just throb more, but I don't want to give up exercising because I know it's important to my body. I really don'g belive anyone knows what to do to help since this disease affects everyone so differently..I just keep trying to find something that will help the aching.