Multiple Sclerosis (MS) Support Group
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Is MS Causing More Damage Than First Thought?
tiredbunni
It's the Tip of the Iceberg: A New paradigm for MS.
The diagnosis of secondary progressive MS has long been thought to mark a shift in the course of the disease from a primarily inflammatory process to a neurodegenerative one. Although the
majority of people with MS are initially diagnosed as relapsing-remitting, about half of them, after ten years, will transition to a secondary progressive disease course. This progressive phase is
characterized by gradual loss of function and thought by some to herald a shift.
A conversation with Dr. Tim Vollmer about our evolving understanding of MS by Pat Daily, LCSW The diagnosis of secondary progressive MS has long been thought to mark a shift in the course of the disease from a primarily inflammatory process to a neurodegenerative one. Although the majority of people with MS are initially diagnosed as relapsing-remitting, about half of them, after ten years, will transition to a secondary progressive.
It basically says that there is more gray matter being damaged during RR phase. And that MS likely to attack same area over and over. So with traditional MRI will not pick up on new lesion as they look like the old ones. The inflammatory phase is occurring in secondary phase. The major target of the immune attack is not the myelin but the CNS. It also states that during "remission" MS is quite active during that phase.
Read more at link. It is in PDF format.
http://www.creditcards-onthego.com/Vollmer interview MS disease processr 09 (1).pdf
The diagnosis of secondary progressive MS has long been thought to mark a shift in the course of the disease from a primarily inflammatory process to a neurodegenerative one. Although the
majority of people with MS are initially diagnosed as relapsing-remitting, about half of them, after ten years, will transition to a secondary progressive disease course. This progressive phase is
characterized by gradual loss of function and thought by some to herald a shift.
A conversation with Dr. Tim Vollmer about our evolving understanding of MS by Pat Daily, LCSW The diagnosis of secondary progressive MS has long been thought to mark a shift in the course of the disease from a primarily inflammatory process to a neurodegenerative one. Although the majority of people with MS are initially diagnosed as relapsing-remitting, about half of them, after ten years, will transition to a secondary progressive.
It basically says that there is more gray matter being damaged during RR phase. And that MS likely to attack same area over and over. So with traditional MRI will not pick up on new lesion as they look like the old ones. The inflammatory phase is occurring in secondary phase. The major target of the immune attack is not the myelin but the CNS. It also states that during "remission" MS is quite active during that phase.
Read more at link. It is in PDF format.
http://www.creditcards-onthego.com/Vollmer interview MS disease processr 09 (1).pdf
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http://www.creditcards-onthego.com/MS.pdf
Thanks for posting it.