I have to answer my own question and say that yes, this has now happened to me. After 3 wks of feeling miraculously fantastic, I crashed on Friday. I woke up feeling more horrible than I have since starting any treatment at all. I have now been cutting my 5 mcg pill in fourths and taking only three of the four quarters throughout the day. Thankfully I'm already feeling a bit better. Why does proper treatment for hypothyroidism have to be so difficult?

Hi Ralpert...I am a new member just on Levo for 12 days. Have you been on T3 only or both?

Hi ThusFar. I'm on both T4 and T3 - 75mcg Levo and 5-ish mcg Cytomel. I was able to play around with my Cytomel dose over 3 or 4 days and began to feel better again. I've learned that I have to pay very close attention to my body's signals throughout the day so that I can adjust my next dose and make sure I don't get too much again.

Are you feeling better on the Levo yet? When I first started, it took 10 days before I felt the benefit of the T4.

The information is a bit misleading. Here's the issue: Everyone is different, but there are some guidelines that hold true for -most- people.

For -most- people your Free T4 should be in the upper part of the range (60-100% of range) and your Free T3 should be above 50%.

There IS a method to the madness and it takes some effort but it's worth it.

I'll post a link here (if you can't see it - please join the Hypothyroidism Resources Group - then you can see it):
https://www.dailystrength.org/group/thyroid-resources/discussion/sooo-you-039-re-hypo-good-newbie-information

You will have to copy and paste the links because THIS SITE! Ugh.

If you have questions, please post 'em.

PS One thing that -most- thyroid patients report as being helpful is this:

Cut your cytomel dosage in half - take half in the morning, take half around your "afternoon crash" (2pm). Most report this helps alot.

Hello Lovely Flutterby's! I am looking in on you for the first time in MONTHS! The stress of dealing with this re-vamped site is not a good idea for my adrenal issues.

Here is my suggestion: find yourself a functional medicine doctor who will prescribe Slow Release Cytomel at a compounding pharmacy. The T3 remains in your blood stream all day and you don't have to chop up your tiny pill into even tinier bits that you them forget to take on time....

I have done really well with this!

My issues with thyroid seem to now be much better. The only problem right now is low cortisol, which most doctors won't treat until/ unless you get Addison's Disease and are about to drop dead. GGGGGGGRRRRRRR.

I am FINALLY, after 3 years of this crap, convinced that I really DO need to see an endocrinologist - but I will not let that person mess with my thyroid meds.....

Hope you all are well!!!

Hugs!!!

I have now learned that I need a 3rd Cytomel dose in the evenings. I've always had issues with irregular heart beat in the middle of the night. Since that is both a hypo- and hyper-thyroid symptom, I was uncertain if I was overdosing myself on Cytomel or not.

The other day, I forgot to take my afternoon dose until supper time. I then decided to just skip it, go to bed early, and get back on track the next day. I woke up around midnight with a very irregular heart beat, lots of muscle pain, and pretty bad veritgo. By 2am I decided it was only 4 hrs early for my morning dose, so I took it. Within 5 minutes the veritgo went away and my heart settled right down. 5 minutes! About 10 minutes later all the pain went away and I finally fell back to sleep.

So, I've concluded that my irregular heart in the middle of the night is because I am out of T3 and my body is starting to suffer. I'm now taking a 3rd dose of Cytomel just before bedtime and sleeping pretty well for a change.