Hyperparathyroidism Support Group
Hyperparathyroidism is overactivity of the parathyroid glands resulting in excess production of parathyroid hormone (PTH). Increased PTH consequently leads to increased serum calcium (hypercalcemia) due to 1) increased bone resorption, allowing flow of calcium from bone to blood, 2) reduces renal clearance of calcium, and 3) increases intestinal calcium absorption.
Greetings,
I went tot my endo today. My last 24 hour urine was over 400. My calcium was still in "normal" range. My calcium has been elevated as well as normal. Either way, PTH is now 100 and my Vitamin D is 18 with the Vitamin D 125 elevated at 77. I remember reading about this "conversion" of D to D-125 on the Norman site, but can't say as I really understand it.
She recommended me to an endo surgeon that I will have a consult with and we'll see how it goes from there. She did recommend that I take 12.5 mg of HCTZ so that my kidneys can have a break from the calcium, of course that will elevate my blood calcium levels, so I am not sure what to do? Elevate the calcium, or let my kidneys take a beating in the meantime?
Regards, Brenden.
I went tot my endo today. My last 24 hour urine was over 400. My calcium was still in "normal" range. My calcium has been elevated as well as normal. Either way, PTH is now 100 and my Vitamin D is 18 with the Vitamin D 125 elevated at 77. I remember reading about this "conversion" of D to D-125 on the Norman site, but can't say as I really understand it.
She recommended me to an endo surgeon that I will have a consult with and we'll see how it goes from there. She did recommend that I take 12.5 mg of HCTZ so that my kidneys can have a break from the calcium, of course that will elevate my blood calcium levels, so I am not sure what to do? Elevate the calcium, or let my kidneys take a beating in the meantime?
Regards, Brenden.
Yes, she told me the downside was elevated calcium, though since my levels aren't that high, I suppose she was weighing the benefit/risk. I would hate to get stones, but I also know I felt worse on the HCTZ when I was taking it for my BP.
Regards, Brenden.
Did you have an aldosterone/rennin test?
Have you seen a Nephrologist for kidney issues then?
Brenden, hope you don't have too much of a delay before you see the ENDO surgeon
Regards, Brenden.
I might say something like, "How about we skip the HCTZ, I drink a ton of water, and you get me that surgical consult MONDAY, now that I'm seriously ill?"
But, I'm snarky like that.
Regards, Brenden.
Yeah, I haven't updated because there was a delay. The surgeon said probably hyperplasia and I am scheduled to see her this Thursday again. She wanted to see if the ectopic adenoma was just a weird salivary gland, so they did a 4d CT and said it was just a submandibular gland. However, I saw the ultrasound report as well as the CT and it said there was a nodule on my thyroid that was "echogenic" or something like that. Also, I have bilateral reactive lymph nodes. So, I guess we'll be discussing that as well. Will update when I know more.
Thanks for asking!
Regards, Brenden.
My Endo ordered a 24-Hr Urinalysis and my calcium levels also came back above 400 mg, 404 mg according to the lab result. Were your sodium and creatinine levels normal in this test?
My Endo, however did not suggest putting me on HCTZ. He is sending me in for a KUB X-ray first to check for kidney stones first. Have you been checked for or had kidney stones?
Do you know if the Vitamin D (1,25 Dihydroxy) was "total" or "bioavailable"? It's odd that your Total 25-Hydroxyvitman D (25OH Vit D) is low but your (1,25 Dihydroxy) is high. I've read where high levels of PTH can stimulate overproduction of 1-aplha Hydroxylase in the kidneys which creates high levels of the Vit D (1,25 Dihydroxy).
Anyways the Vit D (25OH Vit D) is the level from what your body creates from sun exposure or consumes and it is stored in fat cells. The Vit D (1,25 Dihydroxy) is created by the kidneys from the stores of Vit D (25OH Vit D) and can then be used by your cells for various processes.
From this I understand that Vit D (25OH Vit D) levels are used to diagnose dietary deficiencies or gastrointestinal and liver disorders. But the Vit D (1,25 Dihydroxy) is used to indicate kidney related disorders, granulomas, diabetes insipidus, genetic problem, or primary hyperparathyroidism.
Yes, they did check creatnine. All I heard from them is that the ratios are fine and that my kidneys are handling the load okay for now. Whether or not I have stones or stones forming I cannot say. According to the Norman site, vitamin D levels are typically low in in PHPT (his data shows a mean of 18) and that the D-125 tends to increase, for whatever reason (mine is 77 out of a max of 75) Don't know about whether it was total or bio. It was Vitamiin D 25 OH Serum. That's all I see.
Regards, Brenden.