Hyperhidrosis Support Group

Primary hyperhidrosis is the condition characterized by abnormally increased perspiration, in excess of that required for regulation of body temperature. Some patients afflicted with the condition experience a distinct reduction in the quality of life. Sufferers feel at a loss of control because perspiration takes place independent of temperature and emotional state.

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Skin & Hair
/ Hyperhidrosis Support Group

palmar plantar HH

sweaty
sweaty

I have been taking glycopyrrolate for about 6 years now. Lately I have noticed that I am sweating more during the day than I have in a while. I always take 2mg before bed. Does anyone know if it works better if taken in the morning? or should I consider talking to my doctor about taking it twice a day?

jagjjb
jagjjb
Be careful with that type of medication, it has been linked to Alzheimer's.
jagjjb
jagjjb
Be careful with that type of medication, it has been linked to Alzheimer's.
runningonhope
runningonhope
i took glyco for about 20 years and stopped because it wasn't as effective anymore and wanted to try to fix the HH naturally. i assume the drug must have some side effects the doctors don't know about especially after taking it for so long. i would set my alarm at 7am every morning to take my 1mg glyco pill. 7am was my sweet spot. i originally took a second pill in the afternoon but it wasn't needed so i just stuck with the morning pill. if i took it late or earlier it would increase my sweating so i'd take a second and it might help. another reason i stopped taking it was because i noticed my stomach was bothering me and got worried about side effects.
ghost12345
ghost12345
Hello,
I used to take Rubinol 1 time after breakfast, and again before bedtime. It seemed to work decent for a while, but it's not full-proof.
I also used Drysol for my palms every night before bed.
alylee
alylee
Hmmm... I'm on 6mg a day and still sweat but not dripping from my hands like i normally would be if i wasnt on the medication. I took 7mg or 8mg yesterday (i cant remember) and my hands seemed to almost dry up? Unless it was just because i was relaxed. idk. im trying 8mg today. of generic Robinul
Bethany_03
Bethany_03
Hi, I've been on this generic too for about 2 years. My Dr. gave me 1mg pills to increase as needed. I have noticed it's not nearly as effective as it had been when I started - regardless of times or religious routines I've tried. I even increased my dose to 3mgs in 24 hours and all I get is scaly legs and a bloody nose - with the same nuisance of sweating. My head also feels "plugged" when I'm on it like a summer head cold. Not to mention the horrible fatigue if I take too much. I start feeling like a clumsy, lethargic zombie.

I really thought when I started that I had finally found something that would help - outside of surgery and expensive botox. I was diagnosed at 4 years old and have had to deal with extreme hand/foot sweat for the last 28 years. Which has continued to develop into lower back, thighs and, of course, always in armpits. It is a real drain and I guess I am back to square one because I can't vouch for any medications or topical treatments anymore. :(
I should mention too I am very health conscious with no other interactions. I don't take any other medications outside occasional sodium naproxen for pain.
I am vegetarian, very healthy and exercise, but this medicine makes me angry and still sweaty. I am not sure what else to try as it just feels useless at this point. My thoughts are your body adapts to it and just works around it somehow.