i just recently posted pretty much the same question, you may want to look at the thread, a lot of different view points. I'm also struggling with the decision.

All of your reasons for me, plus since I've had a transplant, nothing is available to me except the standard Interferon/Ribo. I'm also A1, TT, and even though the doctos have told me the best I can expect is to slow down the hep c some, hoping for a better treatment to come along, they are still wanting me to do it. So I might slow it down a little, but be sicker. Is that what I want? At my age, so far, it's not what I want.

I have tried two times and failed. That dang TT gene.

I need to treat and get rid of this virus but the only trial currently available for cirrhotics contains interferon and my doc told me this week that I couldn't take interferon again. I was under the influence of drugs so I couldn't ask him why and my husband didn't think to ask him.

If my liver were in good shape I would definitely wait for easier, better drugs to hit the market.

I was also sure I would be too sick. I waited and went into an all oral clinical trial. No side effects and was undetected day 9. But found out my fibrosure test has me close to cirrhosis. Maybe I should not have waited.

Its pretty much a personal choice,after listening to what the doctors have to say.My doctor told me you need treatment.And its better to get treated while you are semi in good health,and still young.If I wait 3 to 4 years there is a chance I could develop cirrhosis.Treatment has been rough.

One thing to consider is if you can afford not to work if you were unable to. Especially the 48 week tx.

Starcraft has it right it's a personal decision. I waited 11 years since being diagnosed for a better TX. That became approved June 2011, to what is presently 3TX. 11 years! I started TX in March and I end Aug 24. I was undetected at 4 weeks. I worked through my TX. It was an excellent decision for me.

Hey Brigid ment to add. Everyone who is thinkin of TX asks that same question. Why do some do TX? Why do some not TX? For a lot of the people it comes down to whether or not they have ins? If they would have to do clinical trials? If they are in a small town? If there is a major hospital nearby?

I did 24 weeks of treatment for 1a, and cleared. I don't trust big pharma either, but it's either them or HCV.

36 days after treatment, I'm about 80% of normal. It's rough going, but totally worth it.

BUT, if your liver is healthy, you could wait for a more effective treatment. At least a dozen are in the pipeline.

Among my reasons I've already mentioned for not treating is the fact that I lost what body fat and muscle mass I had when I had my transplant 2 years ago and can't gain it back. Except for the fluid I'm retaining, I am skin and bones, and my doctors say I would lose at least 20% of my weight while doing treatments. I don't have weight to lose.
Have most of you lost weight during txs?

I tried the 2x tx, 48 weeks of hell for me. I waited about 5 yrs to tx, was in denial.........
Some seem to breeze right thru it, no/minimal sides... I had a hell of a time. It IS a personal choice and we all have our own beliefs and reasons if we tx or not.
Now I wait, for a milder, gentler tx w/o interferon.
I don't know and don't want to know what shape my liver is in... as there is NOTHING I could do differently than the way I am living now.
Sometimes, we just need to face our fears and move on and live for today! It is, all we have!

I want to treat soon, My body is fighting the virus well, and I feel great most of the time, run half marathons etc... BUT....I know my immune system is being considerably worn out. i get more fever blisters more frequently, I get fungal infections easier and all that fun stuff. SO I absolutely want to treat, I don't want to know what other Extra-hepatic joys await me around the corner!