Hepatitis C Support Group
Hepatitis C is a blood-borne viral disease which can cause liver inflammation, fibrosis, cirrhosis and liver cancer. The hepatitis C virus (HCV) is spread by blood-to-blood contact with an infected person's blood. Many people with HCV infection have no symptoms and are unaware of the need to seek treatment. Hepatitis C infects an estimated 150-200 million people worldwide.
We conclude that adding ribavirin or extending treatment to 24 weeks did not significantly improve SVR rates, Afdhal said. The presence of NS5A mutation had minimal clinical effect on SVR.
Afdhal added that ribavirin did not alter viral kinetics or prevent relapse.
Extending treatment doesnt make clinical or fiscal sense, Afdhal said. We should not over-treat these patients. Twelve weeks in cirrhotics and treatment failures or treatment-naive patients makes the most sense
http://www.healio.com/hepatology/2014-easl-resource-center/ion-2-longer-sofosbuvirledipasvir-treatment-may-be-unnecessary-in-previous-failures
Afdhal added that ribavirin did not alter viral kinetics or prevent relapse.
Extending treatment doesnt make clinical or fiscal sense, Afdhal said. We should not over-treat these patients. Twelve weeks in cirrhotics and treatment failures or treatment-naive patients makes the most sense
http://www.healio.com/hepatology/2014-easl-resource-center/ion-2-longer-sofosbuvirledipasvir-treatment-may-be-unnecessary-in-previous-failures
Think of those of us who did 78weeks of soc, because weren't getting a good response. Adding 24 weeks of more torture and still relapsing or never achieving undie - heartbreaking.
Wish it had worked. Have 2 Respect all who battled with old weapons.
SOC kicked me so bad, I could not do 48wks they had to pull me @ 12wks.