Hi! It's probably because of such a high starting dose and then bringing you all the way down to 450. You are bound to have side effects from that. Make sure you have levels checked a month after starting the new dose. You can go hypo quickly if levels keep dropping. You want to avoid that.

It could be that you are ready for a dose change again. Ask for another tests of the Free T3, Free T4, and TSH. 450 mg of PTU is the equivalent of 45 mg of Tap or Methimazole here in the States. PTU is weaker than Tap or MMI, but for some people can be very sensitive to changes.

I know of few people here on this board and other thyroid boards who find that they must get labs every two weeks and do the dose changes then rather than the usual four to six weeks as they are that sensitive. All this while they try to keep the Free Ts at mid ranges.

You have to remember that you went from very, very hypER two weeks ago and then to experience changes so rapidly from the hypER state to normal and/or hypO state can be just as dramatic.

Another possibility is that you may not no longer need as much Propanolol as you did before as your thyroid levels are normalizing. You will know this if the Free T3 starts dropping to low.

{{{hugs}}}

Thanks so much. I did call my endo and he said that my thyroid levels were still trying to get back to normal and to "hang in there" for a couple weeks. I do have labs being done the week after next (2 weeks from now). My propanolol was three times daily at 40 mg but my bp was so low the last couple days, I tapered down to twice daily as of yesterday. My endo says these are all symptoms that I may experience over the next couple weeks although I have made a remarkable recovery so far. But I needed to hear it from those who have been thru it.... thanks so much! He lowered me from the 1200 to 450mg because he said my levels dropped so fast, closer to normal and I gained 4 pounds in like 2 days. He did mention that we may change my dose at my next appointment but to hang in there.

Hugs!

Yes and it could be that since you dropped one of the doses for the Propanolol may explain why you are feeling this way as well.

Hang in there...{{{hugs}}}

I just looked back on my labs from the beginning. I also had a thyroid storm before diagnosis. I was put on 300mg of PTU. Wow...1200 mg is very high. I agree..watch for hypo! I went hypo in my 3rd month of being on PTU and kept there for almost a year...it really sucks.Getting labs every 2 weeks in the beginning is wise.

I also had sever dizziness at the beginning. I never really did find out what caused it but I suspect it was the beta blocker and being hypo. Once I leveled out and got off the beta's it cleared up. It should for you to. Just give it a bit of time.Big Hugs...Kathy

I always watched my pulse and bloodpressure while on PTU.My doc let me adjust my meds based on symptoms.

Ive had bouts of Vertigo when hypo and hyper. Altho my endo says there is no connection to it and Graves my ENT disagrees and says there is a connection.

oh for sure....for me it was when my dose was increased.

Hello I have also started having dizziness more and more lately. Not sure why this is happening now been doing ok with graves, this just started now.

I just started tapering (somewhat) my beta blocker, & I noticed I was extremely dizzy & tired..

I went from 100mg to 25mg twice a day. I also have WAY more energy. I would take my resting heart rate & it went from 45(way to low) to being reg at 78 lately. & it's only been three days! Of course anxiety comes back (not as horrible,) but I am feeling better. Check with ur docs about the beta blocker. :)