I haven't experienced Nexium but I have tried Protonx and didn't have any problems w/ it. Not sure how often you have to take your PPIs but I only had to take Protonix once a day up to two hours before bed time. If I didn't eat enough dinner I was a bit hungry overnight but a late night yogurt or fruit helped with that.

Also, when you switch medicines for GERD are you also doing the diet change that goes w/ them? like no caffeine no spice, no tobacco, no fried or fatty foods, chocolate no tomatoes, grapefruit or other ascorbic acids. I know some ppl w/ GERD like my mom had to gradually cut back on the fried foods, caffeine grapefruits etc before she was able to cut them out completely.

Also, have any foods like organics or soy products helped? My mom drinks a lot of Soy milk and Almond milk and really likes it. Also, I hate Vitamin D so I drink 2% milk. Watering down products also helps me too. Like drinking soda w/ water or eating a bowl or cup of ice cream w/ a half of cup of milk in it.

Please also be sure that you aren't taking too many vitamins in addition to your regular meds because too much iron or sodium in the body can make your stomach upset too. At least that was the case for me.

GOOD LUCK, I hope you are able to find some relief soon :D

I recommend Nexium. It is the only PPI I've tried that has worked long term for me. I've been taking it for a year now along with the type of diet changes that SweetPea09 mentions, and I have had no more pain.

yes have tried the diet changes. It doesn't seem to matter what I eat. I was told to take something out of the diet, see if you get better and if you do then try that food again. If you get pain then that means its that. But I have pain all the time. doesn't matter what I eat. Do I need to cut them all out at the same time?

I am going to ask the doctor about Nexium and Protonix today.

The only way I got relief was to cut them all out at the same time. It's difficult to do, but it was worthwhile when the pain stopped.

Yeah, I agree w/ Jen, I cut out all the foods that aggravated my acid reflux disease and it made me feel better too. It is a bit hard at first but after a while you don't miss them either

Try Aciphex. It's the only one that worked for me. But try to get off of all of them as soon as you can. I was on for nearly 10 yrs and getting off was HARD. Had to go to a naturopath to do it. But I already had osteoporosis from taking the crap. Strict diet. Raise head of bed. Sleep on L side. Eat celery. I also find my vegan, very low fat (for cholesterol) is very helpful for my digestion.

well I went to the docs last night. She said that it is likely if I havent responded to two ppi's (prevacid and prilosec) then it is likely that GERD is not the cause of the problem but prehaps a symtpom. I asked about Nexium or Protonix but she said it is best to wait until Wednesday when I see the specialist and see what he suggests. I have had an ultrasound and it didnt show up gallstones but am going to ask him to check that further as the extra wind and the pain all round suggests that to me