REposting link in case it will now hotlink for others, didn't for me: https://www.ncbi.nlm.nih.gov/pubmed/28260944

I find this paritcularly interesting b/c I take celecoxib as my *one* Fibro drug. (Yeah, woot.) I do think we've debunked the viral causation theory when it comes to the X-whatever, b/c the lab contaminated its samples and finally had to admit that they couldn't replicate results. *BUT* the number of us with latent EBV, for example, or who've had chicken pox/shingles.... Frankly, I'd try this out.

Thanks for posting!

Thank you for sharing, Shakota! That is very interesting.

If anyone dislikes reading a paper's abstract, the short version:

A research team has further probed the hypothesis of reactivating herpes virus being an underlying cause of fibromyalgia.

143 fibromyalgia patients were enrolled in a placebo-controlled study (I read several older papers where the sample size was under 50, so this was a bit better, at least) . People either got the placebo, or a 1:1 mix of a common anti-viral against herpes (famiciclovir) and a common anti-inflammatory (NSAID) used for treating pain and inflammation (celecoxib).

They administered questionnaires about pain levels and depression at the start and on several occasions in the trial. The results are that those not receiving a placebo had good rates of reduced pain and increased sleeping rest.

The words "significantly improved" were thrown around a lot by the writer of the paper, saying it could prove to be an effective and novel fibromyalgia treatment.

Very interesting indeed!

Thanks shakota and Leo for reposting.

Hi Shakota. I actually read about this study recently. I see an integrative medical doctor and most of them believe that one of the root causes of fibromyalgia can be bacteria, viruses, and candida. They actually test for many of the viruses listed in the study. The premise is that most of the population have been infected by EBV, Herpes Simplex 1 (cold sores) and HHV6, and these infections are never eliminated from the body; rather they instead lie dormant until something triggers them to reactivate. It's kind of like how the chicken pox virus (which is part of the herpes family) never leaves the body, it instead lies dormant and causes shingles later in life. Herpes Simplex 1, which causes cold sores, actually lies dormant in the body and reactivates at various times. The EBV virus also lies dormant within the body. In normal people the viruses just lie dormant and their immune systems keep the viruses in check; however, those with fibromyalgia and CFS have immune system dysfunction so the viruses become active and cause a whole host of body wide symptoms.

I truly believe that bacteria, viruses, and candida are possibly at the root cause of fibromyalgia and CFS.

Thanks for the info! I had candida bad when I had the onset of FMS and PsA, I am a firm believer that this maybe one of the possible culprits! I wonder if mold might also be a culprit, I am very sensitive to molds also.