I took it for a while and felt worse. My mom, who's been dx'd with FM less than a year and is 70, takes it and feels what she calls "about one-tenth of a point improved". And I worry about "associated".... I mean, do people with these issues have low CoQ10 b/c of the illness, or the meds for the illness, and are they trying to imply causation? OK, done fussing.

Worse and a tenth of a point averages out negative. LOL

My neurologist put me on that combined with B2, and D3, to improve my memory.

I put myself and my husband on this combination and my husband has really improved in his ability to think more clearly and remember things much better. I am hoping I improve, they just changed my meds around so after I adjust to the new meds I will know better.

Hope it helps you.

Lots of weasel words in that abstract. I'd like to see the study.

Call me skeptical, but first, fibromyalgia is not a "neuro degenerative disorder," and second, with all the studies floating around, I've never seen one in a peer reviewed journal that "associated" it with CO Q10.

Last time I looked it was really expensive, too.

Not able to take it. My stomach acts like I just swallowed a live volcano.

I took it for a year back in 2007 I think. I found no benefit nor any side effects.

I tried it once, some years ago and within 30 minutes of taking I felt like I had the flu for 2 days.

Thinking that perhaps I did have the flu, I tried it again a month later and was as sick as a dog. I did not try it again

Yes, I take co q10 along with my other supplements. I cannot comment on whether it works alone, as I feel that all of my supplements work in conjunction with one another.

I have been on it for about one and a half years, along with my other supplements. My first integrative medical doctor put me on it, so I continue to take it. He was instrumental in helping me to get my pain levels down from a daily 10 to a 5 with his regimen; so I figured that the entire regimen must be working, so I stayed on it.

I see a different integrative doctor today and am on a different regimen, but kept part of the first doc's regimen. She has helped me to get my pain levels down even further. I feel that both regimens combined have given me the greatest benefit.

Emily I ran across this abstract as well. As I understand it, those of us who have fibromyalgia, have problems with our mitochondria functioning normally. It seems that the mitochondria does not clear up waste products. This toxic waste builds and cannot be eliminated effectively. The mitochondria are considered the power house of cells, especially the muscle cells. Coq10 is thought to help by removing waste products from the cells. This does not mean that taking coq10 will reduce our pain; however, it is thought to help with the removal of waste to help our muscles function better.

Coenzyme Q10 depletion in medical and neuropsychiatric disorders: potential repercussions and therapeutic implications
Coenzyme Q10 (CoQ10) is an antioxidant, a membrane stabilizer, and a vital cofactor in the mitochondrial electron transport chain, enabling the generation of adenosine triphosphate. It additionally regulates gene expression and apoptosis; is an essential cofactor of uncoupling proteins; and has anti-inflammatory, redox modulatory, and neuroprotective effects. This paper reviews the known physio- logical role of CoQ10 in cellular metabolism, cell death, differentiation and gene regulation, and examines the potential repercussions of CoQ10 depletion include- ing its role in illnesses such as Parkinson's disease, depression, myalgic enceph- alomyelitis/chronic fatigue syndrome, and fibromyalgia. CoQ10 depletion may play a role in the pathophysiology of these disorders by modulating cellular processes including hydrogen peroxide formation, gene regulation, cytopro- tection, bioenegetic performance, and regulation of cellular metabolism. CoQ10 treatment improves quality of life in patients with Parkinson's disease and may play a role in delaying the progression of that disorder. Administration of CoQ10 has antidepressive effects. CoQ10 treatment significantly reduces fatigue and improves ergonomic performance during exercise and thus may have potential in alleviating the exercise intolerance and exhaustion displayed by people with myalgic encepholamyletis/chronic fatigue syndrome. Administration of CoQ10 improves hyperalgesia and quality of life in patients with fibromyalgia. The evidence base for the effectiveness of treatment with CoQ10 may be explained via its ability to ameliorate oxidative stress and protect mitochondria.
Mol Neurobiol. 2013 Jun 13. [Epub ahead of print]

If you decide to take this it any other supplements - research the company who makes them. You do not want synthetic vitamins, your body doesn't know what to do with them.

IMO whole food vitamins are the best, if you can't get the vitamins from your food. Your diet is also extremely important.

GOOD LUCK

Thank you, Space girl. I am working very hard on my diet because I assume that like everything else about us, our ability to make the most of what we eat is also compromised. Else, why would so many of us have low d and low, b levels?