COPD & Emphysema Support Group
COPD is a progressive disease characterized by airflow obstruction or limitation. Emphysema is characterized by loss of elasticity of the lung tissue, destruction of structures supporting the alveoli and of capillaries feeding the alveoli. Both have symptoms that include shortness of breath, among other respiratory troubles. If you are a COPD or Emphysema sufferer, join...
Neuroprotectors May Prevent Premature Aging of Lungs In COPD
COPD has been described as a disease of accelerated aging. A recent article published in the International Journal of Chronic Obstructive Pulmonary Disease suggests that geroprotectors may help prevent the premature aging of the lung that's associated with COPD. But, what are geroprotectors and how do they work?
Neuroprotectors, such as melatonin, metformin, rapamune and resveratrol, are believed to be anti-oxidant or anti-aging molecule regulators, meaning they work to fight against the aging process. Recent studies suggest that accelerated aging plays a major role in COPD and that geroprotectors may actually stop the progression of COPD.
Although further investigation is needed to test this theory, authors of the article conclude that geroprotectors should not be used to extend lifespan in COPD, but to prevent premature aging of the lung that is caused by exposure to environmental airway irritants which act as oxidants once inhaled.
Where can you find geroprotectors? Before attempting to purchase any of these substances, check out the following and then talk more with your doctor:
Melatonin -- A popular hormonal supplement found in many health food stores. Best known for regulating sleep, but has many other important uses and benefits, as well.
Metformin -- A medication used by diabetics to help control high blood sugar. Also used off-label for weight loss, polycystic ovary syndrome, gestational diabetes and HIV lipodystrophy syndrome. Available by prescription, only.
Rapamune -- Used to suppress immune response in organ transplant. Associated with many adverse side effects. Has been found to increases life-span of mice and may play a future role in treating cancer, tuberous sclerosis complex, progeria, HIV and polycystic kidney disease. Available by prescription, only.
Resveratrol -- Chemical found in the skin of red grapes and, in red wine. Studies suggest that substance offsets negative effects of high-calorie diet in mice, thus extending their lifespan. But, before rushing out to your nearest wine haven, take into consideration the following: For these experiments, mice were given extremely large dosages, in fact, according to an article in the New York Times, a human being would have to consume 35 to 100 bottles a day to get an equivalent dose. Scientists are looking at ways to concentrate the dosage of resveratrol so it is more appropriate for human consumption.
Source:
Kazuhiro, Ito, et. al. Neuroprotectors as a novel, therapeutic strategy for COPD, an accelerating aging disease. International Journal of Chronic Obstructive Pulmonary Disease. 2012:7 641-645.
You can read more here: http://www.dovepress.com/geroprotectors-as-a-novel-therapeutic-strategy-for-copd-an-acceleratin-peer-reviewed-article-COPD
I thought this was very interesting and thought some of you might think so too.
Have a great easy breathing Friday and Weekend everyone,
Love
Holly
COPD has been described as a disease of accelerated aging. A recent article published in the International Journal of Chronic Obstructive Pulmonary Disease suggests that geroprotectors may help prevent the premature aging of the lung that's associated with COPD. But, what are geroprotectors and how do they work?
Neuroprotectors, such as melatonin, metformin, rapamune and resveratrol, are believed to be anti-oxidant or anti-aging molecule regulators, meaning they work to fight against the aging process. Recent studies suggest that accelerated aging plays a major role in COPD and that geroprotectors may actually stop the progression of COPD.
Although further investigation is needed to test this theory, authors of the article conclude that geroprotectors should not be used to extend lifespan in COPD, but to prevent premature aging of the lung that is caused by exposure to environmental airway irritants which act as oxidants once inhaled.
Where can you find geroprotectors? Before attempting to purchase any of these substances, check out the following and then talk more with your doctor:
Melatonin -- A popular hormonal supplement found in many health food stores. Best known for regulating sleep, but has many other important uses and benefits, as well.
Metformin -- A medication used by diabetics to help control high blood sugar. Also used off-label for weight loss, polycystic ovary syndrome, gestational diabetes and HIV lipodystrophy syndrome. Available by prescription, only.
Rapamune -- Used to suppress immune response in organ transplant. Associated with many adverse side effects. Has been found to increases life-span of mice and may play a future role in treating cancer, tuberous sclerosis complex, progeria, HIV and polycystic kidney disease. Available by prescription, only.
Resveratrol -- Chemical found in the skin of red grapes and, in red wine. Studies suggest that substance offsets negative effects of high-calorie diet in mice, thus extending their lifespan. But, before rushing out to your nearest wine haven, take into consideration the following: For these experiments, mice were given extremely large dosages, in fact, according to an article in the New York Times, a human being would have to consume 35 to 100 bottles a day to get an equivalent dose. Scientists are looking at ways to concentrate the dosage of resveratrol so it is more appropriate for human consumption.
Source:
Kazuhiro, Ito, et. al. Neuroprotectors as a novel, therapeutic strategy for COPD, an accelerating aging disease. International Journal of Chronic Obstructive Pulmonary Disease. 2012:7 641-645.
You can read more here: http://www.dovepress.com/geroprotectors-as-a-novel-therapeutic-strategy-for-copd-an-acceleratin-peer-reviewed-article-COPD
I thought this was very interesting and thought some of you might think so too.
Have a great easy breathing Friday and Weekend everyone,
Love
Holly
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My 6mo twin DD's are EBF and just started rice cereal on the first. Everything has been going fine except this morning one of them had a diaper rash (lots of redness around her anus). I read this as one of the signs of an allergy. BUT I did just buy a different brand diaper yesterday (which they have used randomly before w/no issues). Do you think its the cereal or the diaper? Im ready to start...
Curt ;)