Thanks! Love any info that makes is more clear.
The mitochondrial aspect isn't new to me but hey any research is good research!

So, I'm interested. I've been taking magnesium, 1000 mg a day for years. Works great. I own powdered D-Ribose... I can't find info on how much d-ribose to take and if it should be taken empty stomach or with food etc. Will you share how you take it as you have had some success?
thanks

Had trouble getting to the right site. Is the the article you were referring to?
http://drmyhill.co.uk/wiki/CFS_-_The_Central_Cause:_Mitochondrial_Failure

From what I've read in a book on D-ribose that is basically for heart patients, you can take up to 60 grams a day. I usually take around 20 grams in the morning, and if I'm dead, I take extra. In the last couple of days I've probably taken the 60 grams a day [spread out over the day], and while I'm tired, I'm not completely exhausted like I used to be.

I take it in powdered form and put it either in juice, on cereal or with yogurt.

I'm a total fan of Dr. Myhill. I've read books on Mitochondrial dysfunction and am totally in agreement with our energy cells being broken as a cause of our extreme exhaustion. I enjoyed the article very much.

I especially liked how she showed how this dysfunction effects so much more than just our energy supply! This disease affects our hearts, liver, gut....you name it. Yet, very often we don't look sick. I know we all get tired of hearing people tell us that!

Thank you for posting this article. I immediately e-mailed it to my future SIL who has moved in with me. I want him to learn about my "strange" behaviors and quirks and learn that none of this is in my head.....before the thought ever even enters his mind! You can't live with someone who doesn't believe in the devastation of CFS. You can't!

Hello, it is nice to meet you. I couldn't find the article you were highlighting but believe me with my brain fog that is not uncommon. I did bookmark the site because there were several articles I want to read. I too was dx'd with Fibro first because I have 14 of the 16 tender points but I never felt that was right. Once I had received my CFS dx, actually the second time I received it, I knew I had my answer.

Welcome to the site, this is my favorite group of people on a CFS forum, very supportive & I know they understand me. I hope you have a good experience here as well. Hugs, Denise

When I was diagnosed with fibro 10.5 years ago my Rheumy told me the treatment was 'exercise, exercise, exercise and sleep' so I went home and started exercising even more than I already was--have always tried to stay in shape. Finally, after long crashes where I couldn't do anything, my husband convinced me that I needed to listen to my body and if I didn't feel like doing something, not to do it. I can remember reading a book on running when I was in my early 20s saying how if you're tired, exercise will perk you up. For a normal person that's true, but for us it's a recipe for disaster!

Another interesting comment in that article was about how you stop sweating. I went through that for years and finally one of the naturopaths I saw had me sit in front of a heat lamp to stimulate sweating--we built a near infrared dry sauna that was just a heat lamp on a board on a stand that I sat in front of. Before that, it had to be 100 degrees before I broke into a sweat. Now I sweat much easier.

Nina, I'm reading Dr. Teitelbaum's book "From Fatigued to Fantastic"; he's a huge fan of D-ribose. His regimen is 5000 mgs -- 5 grams! -- 3x a day for 3 weeks, then the drop back to 5000 mgs 2x/daily. He says you'll know if it's working for you by the end of a 280 gram container.

I just ordered some.

I've also got Dr. Teitelbaum's book because the doctor who is treating my CFS follows his protocols. Interesting though that my doctor never mentioned d-ribose to me since Dr. Teitelbaum says that's one of the first things he has someone with CFS try.

My doctor is prescribing hydrocortisone 20 mg daily that I take with breakfast so I wonder if that supersedes taking d-ribose? I'm seeing my doctor next week Friday so I'm going to ask him about d-ribose and CoQ10 that Dr. Teitelbaum also recommends. Anything that could help my energy levels seems worth a try ~

Thanks Jack - I have the book in the house, I'll revisit - it's been a while. I put it away when I failed to feel "fantastic" :-/ But every little bit helps.