Zoloft worked for me for several years. It helped stop the anxiety and the circular, cycling thoughts. It also contributed to weight gain -- about ten pounds. Eventually, my pdoc had to take me off Zoloft because I went through a "poop out" (i.e. the Zoloft stopped working and I became symptomatic again).

Your mileage my vary.

oops. forgot to add that, yes, Zoloft can increase your appetite, at least at first. You might start to crave carbohydrates. I know I did.

It's been years since I've taken zoloft....but I do remember the doc saying that alot of Ad's can cause about 10 pounds of weight gain....NOTHING like the AP's that we take!! I'd give it a whirl, my friends takes it and does real well on it!

I am taking it right now and I don't think it is working for me. Oh well. Medications are individual, what works for one person does not work for another.

I have been taking it for about two years. It works for the anxiety - to a certain extent.

When I first started it, I had alot of nausea. That passes, but I actually lost weight on it.

My niece thinks it should be put in the drinking water so everyone can have a dose!! HA!!

I hope it works for you. MK.

unfortunately it didn't do a thing for me but make me nauseous. it was pretty weight neutral but that might because i just didn't feel like eating when i was taking it. i hope you have good luck with it. it works really well for some people.

I took zoloft with my old cocktail. I did gain some weight on it, but I think it's because it made me crave carbs as perennial mentioned. It made me a bit of a zombie, but not as badly as seroquel did. It really did help control my symptoms for a while.

I'm on zoloft now, I'm not really sure if it's helping me with depression or not. When you take so many pills it's hard to tell which one is working.

I've lost almost 100 lbs within the last year. When I first started taking lexapro I dropped 35 lbs in a month!
I'm not on lexapro now, but still am having no problem losing weight. I'm about 25 lbs back to my goal of 135! Pretty good considering I've had 8 kids!

I do not recall any weight gain...I think it's actually considered weight "neutral" But I did yawn a lot...even when I was not tired at all. I just yawned all the darn time. We decided it wasn't a good fit for me and moved on, but yeah the only bad thing I can say about it was the yawning....not so bad! That was not a factor in me d/c the med...it just didn't work for me....

I gained a ton of weight on Zoloft. The second I got off of it, the weightt melted away

When I first went on sertraline it made me hypomanic & I hardly slept at all, so my zyprexa dose was upped which did the trick.
It didn't make any difference to my appetite at all. I forget to eat whilst hypomanic & don't feel like eating if depressed anyway. On the whole my appetite has always been the same as it was before I started meds. It's zyprexa that has made me put on weight, even with eating healthily & excercising.
Not sure that it actually works for me but I have zyprexa aswell & sometimes have lorazepam.

Zoloft was my first medication given to me for depression. It is normally a weight neutral type of med.( I see some here gained) It worked well for me with what I needed it for. Depression and OCD. Some other issues. Anyway, never gained. The only problem was that on my way to being diagnosed with BP they stopped it because of the mania. It was the only med that did work for me when on the down side.

Hi..I would love to hear how the sertaline-zoloft works for you and your weight loss. I am still trying hard to lose the 20 pounds that I gained when my doctor perscribed remeron for me. No one told me that it would cause me to gain so much weight. My doctor even suggested that maybe I was eating more because of the depression...but I assured him that I wasn't and that my husband could back me up that I was acutally trying to eat less because of all the weight gain.

zoloft worked wanders for me i was on 50mg for 8yrs then kinda wore off and they upped to 100mg and it sent me into mania....but im still on it...wth lamictal and trazadone...the only thing that sucks it it is very very hard to wean off of....major withdrawls...i culdnt do it so they kept me on it! gud luck

Just want to say thanks for all of your replies! Very useful :)