Atrial Fibrillation (AFib) Support Group
Atrial fibrillation (AF or afib) is an abnormal heart rhythm (cardiac arrhythmia) which involves the two small, upper heart chambers (the atria). Heart beats in a normal heart begin after electricity generated in the atria by the sinoatrial node spread through the heart and cause contraction of the heart muscle and pumping of blood.
I take a vitamin K antagonist (like Warfarin) and am in range (INR between 2 3) 97% of the time.
As far as I know all the studies that compare NOACs to Warfarin use an in time range of 60% or less (no wonder they come out looking better!!). If you are in range a good % of the time and arent bothered by getting your INR checked Id say stay with Warfarin. It has an added advantage: if you should have an accident the doctors are more likely to have more experience as to how to stop the bleeding (Warfarin has been around a long time and is well understood).
If it aint broke, dont fix it.
Carpe diem,
atp
regards
ray
I agree with the comments made so far but would like to add a consideration.
I went to Eliquis because I was travelling. I discovered really quick that getting a blood test to check my INR is not always easy when away from home. I was in the Phoenix area to visit family around a holiday and all of the clinics that were recommended were either closed or booked. I eventually found one but it was a hassle.
I was planning a trip to hike the Inca trail in Peru. No clinics on the trail and I didn't know what kind of food would be available. So I switched. Eliquis was a lot easier than Warfarin would have been.
Every option has it's positives and negatives. With travel, a NOAC sounded much better to me.
Todd
RE-LY was 64%
ROCKET AF was 55%
ARISTOTLE was 62%
ENGAGE AF was 65%
So if your TTR is that or lower than the NOACs are probably a good choice.
(I found the table in the American Journal of Cardiovascular Drugs / Medscape:
http://www.medscape.com/viewarticle/853388 in table 3 of the article Non-vitamin K Antagonist Oral Anticoagulants: New Choices for Patient Management in Atrial Fibrillation)
carpe diem,
atp
So, if your TTR is that or lower, then the NOACs are probably a good choice.
Price is another question due to medicare, but doable with some tweaks of other meds.
laurab