So I listened to my doctor and increased 50mg more of Zoloft to 200 from around July 1st. I have had breakout hives which I thought were mosquito bites st first.  Then I started with such intense leg cramps it made the ones I got when I was pregnant nothing.  I was sore 3 days it was so bad.  Well I thought that was because my feet were cold from the A/C was cold.  
Now I'm lying down after taking the antihistamine- welts are subsiding, and my lip swelled to the point where it's blocking the nostrils so Ive had to breathe through the mouth. 
Doc says not likely it's Zoloft since I've been using it over a year. Here's the clincher... I have swelling on the spine and thank goodness for my physical therapist- opinion that it looks like reaction from meds because it's systematic not local.
Why am I sharing this? Because never doubt yourself, and think doctors aren't the highest power. Even though this doctor's never seen this type of reationVin his 40+ years. Guess I'm the lucky one.