Hi dgn. Good, I'm glad you are trying it! I am curious to know if it helps because that pharmacy PhD is writing a paper on it.

No, 50 mg, is not anywhere near close enough, I don't think. My guess is that these seizure meds work for us at about the level they work for people with seizures. For Mysoline, that is about 500mg and sometimes as high as 750mg. I take 450-500mg every night. I always wake up to T, sadly, but it fades to a volume 1 or 0 when I get up and move around. That might just be something that happens with me.

Oh, with me it didn't take long to work--a few days.

Keep us posted dgn.. If it works for you I will give it a try as well.. Nothing has worked at all for me... Time has been my best friend. However, some small relief would be a great help, just knowing it was there, close by... bob

Yes, it true, 50 mg is not working

I will 100 mg

Not sure I can handle more

DGN, how much will your doc let you go up to? I think I had to work up incrementally like you do with gabapentin or any seizure med...like 50mg every three days, so it took me a month to get to 500mg, but I could tell before I hit that level it was starting to work (maybe at about 350mg?). Why do you say you don't think you can handle more? People with seizures take much more than 50mg. I don't think 100mg is enough--T is a brat and you need all that GABA and glutamate suppression that 400-500mg gives your brain to fight it--but keep us posted! At least it doesn't make you groggy like gabapentin does as you step up.

I should explain that when I said it took only a few days to work, I meant when I hit the 450-500mg level I was working up to. That's the point when I stopped hearing my T or only loud enough so that I had to listen for it. Sorry, didn't mean to be confusing.

I read somewhere that Mysoline and other seizure meds work best for people who have tinnitus due to an illness which affects the 8th nerve. I'm guessing that for those of us that have it due to loud noise, it may not be effective, but I will be interested to hear of anyone's success stories.

That could be (though that kind of hearing loss is more rare), but all sorts of people with T (I would imagine from a variety of causes) have responded well to an increase in GABA and a reduction of glutamate in the brain in clinical trials. That is one reason Klonopin has done so well in clinical trials for lowering T volume (a GABA enhancer).

McMurdo, this med is strong. I juts took .75 last night.

A little bit of improvement. I will take 100 mg tonight.

If 100 mg does the trick, why should I go past that amount.

I can see that 450 mg would definetly work. You can tell, that this med

definetly helps lower you tinnitus. But the flip side is, that we might

have to on this stuff for at least two more years, when I feel

from the CLA studies, that they will have three projects

ready to roll out, to attack Tinnitus. And, I don' think my DOC, wants

to risk giving me that much mg.

I meant to say the three UCLA studies (or seminars I have attended)

Dichonics Inc.
MEG
Micro Transponders

I'm interested as well. Mc, that is WONDERFUL that you get down to a 0 or 1, what a dream come true. I am SO happy for you and hope we all get even half of those results and I'd be grateful.
Sue

Dgn..when is the next UCLA T support group meeting this October? I think I will attend.

Peter

Send a email to Nelly. She will put you on the UCLA seminar list.

WE meet in the middle of the month for 9 months out of the year.

ATA, also has her info.


Nelly Nigro nan_nigro@yahoo.com

We will have a meeting in October.

I thought of attending the last meeting, but didn't make it. Maybe I will this month. I would like to know more about these studies.

Every month, iit is something different