harry, could you please explain the problem a bit more, i don't really understand it, what brand and model have you got?

Good question Harry. It probably depends on the brand and the way the humidifier is set up. I know that on a couple of occasions I have pulled the unit off my night stand and the humidifier portion separated from the CPAP portion and the humidifier ended up upside down. Of course I picked it up quickly and turned it upright, but in those cases there was no leakage. Don't know if left upside down for any length of time would make a difference or not.
Mine is set up so that the air blows into the humidifier and then back out through the hose and so any opening between the humidifier, CPAP and hose is pretty air tight.

Mine fell over a couple of times and each time the water ended up in the tubing. It's a F&P ICON Auto. The tubing is heated as well as the humidifier.

http://www.fphcare.com/products/icon-autoplus/
http://www.fphcare.com/sleep-apnea/cpap-devices/f-p-icon/

ive heard of water from humidifier damaging the electrics in some if picked up the wrong way

its safer with CPAP on bedside table to tie airhose to bedhead, which stops airhose from pulling CPAP onto the floor

Harry, I'm sure it would if it got in the electrical parts as with anything electrical. What brand and model CPAP have you upgraded to?

Yeah, tying the hose to my headboard isn't going to happen. I've used a CPAP for 3 years and in that time I've pulled it off the nightstand twice. And both times were early in my usage.
With adjustable beds (for my husband) and my CPAP gear my bedroom looks enough like a hospital room already.

You'd think they could lengthen the tubing.

My husband put his C-pap machine in the night stand drawer. He had to cut a hole for the hose to go through. It keep him from tipping over the machine.