Rheumatoid Arthritis Support Group
Rheumatoid arthritis is a chronic, inflammatory, multisystem, autoimmune disorder. It is a disabling and painful condition which can lead to substantial loss of mobility due to pain and joint destruction. The disease is also systemic in that it often also affects many extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and...
RA can affect other parts of the body, beside the joints. It is possible for RA to affect a person's nerves and blood vessels among other organs too. Although I am not an expert in RA, I suppose that it's possible that if the RA is affecting his nerves then it could cause the numbness and cold feeling in his feet. But there are also other conditions that can cause numbness and coldness in the feet. For instance, people with diabetes can get that too. So I would say that your concerns are valid, and that it is worth running it by his physician. Perhaps there may be something they could do for it that could give him some relief. Best of luck to you and him!
I get cold hands sometimes and Raynaud's disease is a possibility for RA patients. My mom had that. I don't know if it affects the feet.
you are a good sister.
Homocysteine destroys the endothelial cell layer of the blood vessels. A problem with vasoconstriction would then result. It also destroys the tiny nerve fibers and this would result in numbness. As the following study states, "Elevated levels of homocysteine occur commonly in RA".
http://www.ncbi.nlm.nih.gov/pubmed/9125255
In RA, an inability to break down dietary proteins would result in an inability to metabolize B12 and this would result in elevated levels of homocysteine.