I haven't found anything that helps with the fatigue. I think that is what makes my thought process go haywire at times. I am just so tired. Am looking forward to hearing what others have to say about this. Good luck!

My fatigue got better once I started on Humira. I was ( and still am) on MTX and hydroxychloroquine. It is not gone, but much more tolerable.
I do find it more increased the day after I take MTX, but not nearly what it was before I started on the biologic.

Sleep.

I have a lot of problem with the fatigue from the RD and from my MTX. I think the MTX makes it worse, especially the first few days after taking my injection.

Currently I'm taking MTX, Folic Acid and vitamins. I haven't moved "up" to the biologics yet. My Rheumy did give me a script for Phentermine. I take them on days I work, otherwise I would not be able to get through the day. They are my "energy" meds. I've been off work for the last 2 days, and haven't taken them. I can really tell the difference.

Humira pretty much wipped out the fatigue

I get Meyers IV infusions and AMP5 w/ B12 shots. They are very costly, but they have helped me tremendously.
Insurance does not cover them.

Meyers is basically a cocktail of intravaneous vitamins w/ glutathione.

AMP5 shots help me great deal w/ energy. My doctor even lets me purchase viles of AMP5 and Vit B 12 and take shots at home in between infusions.

They have kept me on my feet. I was dxed w/ chronic fatigue syndrome and spent the first year w/ cfs and ra housebound.

I can now work 6 hours a week.

Thanks for your replies everyone. I wondered if it could be the methotrexate. I've only been on it for 6 weeks or so.

I'd hate to add another pill, but I get SO sleepy at times, even after a lot of sleep.

MTX should improve your situation with more time. Give it three months, if things don't get better, talk to you doctor.