Rheumatoid Arthritis Support Group
Rheumatoid arthritis is a chronic, inflammatory, multisystem, autoimmune disorder. It is a disabling and painful condition which can lead to substantial loss of mobility due to pain and joint destruction. The disease is also systemic in that it often also affects many extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and...
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Can I take etanercept while breastfeeding?
"Etanercept is a large protein, so very little of the medication is expected to pass into breast milk. The medications is also not well absorbed from the gut, so any etanercept that gets into breast milk would most likely pass through the baby’s body without getting into their bloodstream. Premature babies with digestive systems that are not fully developed may be able to absorb more of the medication through breast milk.
"The information on taking etanercept while nursing a child is very limited. Four reports of mothers who breastfed their infants while using etanercept suggest that etanercept levels in breast milk are very low. Two of these reports looked at the amount of etanercept in the baby’s blood from breast milk and found the levels were undetectable. One of the infants was followed to 3 years of age and no harmful effects were reported.
"A small study looked at 5 breastfeeding infants who mothers were treated with etanercept, and compared them to breastfeeding infants who mothers had the same medical conditions but were not being treated with a TNF inhibitor. The study found no differences in the infants’ growth, development, response to vaccinations, or illnesses in the first year of life.
"While the available information is reassuring, the risk to the breastfed infant is still unknown. Be sure to talk to your health care provider about all your breastfeeding questions."
https://mothertobaby.org/fact-sheets/etanercept-enbrel-pregnancy/
Breastfeeding Medicine
Breastfeed Med. 2014 Dec 1; 9(10): 543–546.
Lactation and the Use of Biologic Immunosuppressive Medications
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267708/
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